4CXJ

BTB domain of KEAP1 C151W mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008134	molecular_function	transcription factor binding
A	0016567	biological_process	protein ubiquitination
A	0031463	cellular_component	Cul3-RING ubiquitin ligase complex

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	SITE: Sensor for electrophilic agents => ECO:0000269|PubMed:18251510, ECO:0000269|PubMed:29590092

Chain	Residue	Details
A	TRP151

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: S-nitrosocysteine; alternate => ECO:0000250|UniProtKB:Q9Z2X8

Chain	Residue	Details
A	TRP151

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	CROSSLNK: N5-[4-(S-L-cysteinyl)-5-methyl-1H-imidazol-2-yl]-L-ornithine (Arg-Cys) (interchain with C-151 in KEAP1) => ECO:0000269|PubMed:30323285

Chain	Residue	Details
A	ARG135

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	CROSSLNK: N5-[4-(S-L-cysteinyl)-5-methyl-1H-imidazol-2-yl]-L-ornithine (Cys-Arg) (interchain with R-135 in KEAP1) => ECO:0000269|PubMed:30323285

Chain	Residue	Details
A	TRP151

---