4CW4

Crystal structure of the noncanonical ketosynthase FabY from P. aeruginosa

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004315	molecular_function	3-oxoacyl-[acyl-carrier-protein] synthase activity
A	0005829	cellular_component	cytosol
A	0006629	biological_process	lipid metabolic process
A	0006631	biological_process	fatty acid metabolic process
A	0006633	biological_process	fatty acid biosynthetic process
A	0009245	biological_process	lipid A biosynthetic process
A	0009372	biological_process	quorum sensing
A	0016020	cellular_component	membrane
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
A	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
A	0019290	biological_process	siderophore biosynthetic process
A	0033818	molecular_function	beta-ketoacyl-acyl-carrier-protein synthase III activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 1635

Chain	Residue
A	GLU62
A	ARG75
A	TYR76
A	ARG79
A	HOH2111
A	HOH2797
A	HOH2798

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL A 1636

Chain	Residue
A	SER437
A	THR438
A	ASN441
A	ARG442
A	PHE350
A	ASN353

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: For beta-ketoacyl synthase activity => ECO:0000255|PROSITE-ProRule:PRU01348, ECO:0000305|PubMed:25456814

Chain	Residue	Details
A	CYS281

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site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: For beta-ketoacyl synthase activity => ECO:0000255|PROSITE-ProRule:PRU01348

Chain	Residue	Details
A	HIS434
A	HIS472

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