4CW3

Crystal structure of cofactor-free urate oxidase in complex with the 5-peroxo derivative of 9-metyl uric acid (X-ray dose, 665 kGy)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004846	molecular_function	urate oxidase activity
A	0005777	cellular_component	peroxisome
A	0006144	biological_process	purine nucleobase metabolic process
A	0006145	biological_process	purine nucleobase catabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0019628	biological_process	urate catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MPD A 1303

Chain	Residue
A	GLN158
A	TRP174
A	SER192
A	HOH2393
A	HOH2468
A	HOH2515
A	HOH2617

---

site_id	AC2
Number of Residues	13
Details	BINDING SITE FOR RESIDUE MUA A 1305

Chain	Residue
A	THR57
A	ASP58
A	PHE159
A	LEU170
A	ARG176
A	SER226
A	VAL227
A	GLN228
A	ASN254
A	XDS1302
A	OXY1304
A	ILE54
A	ALA56

---

site_id	AC3
Number of Residues	15
Details	Binding site for residues XDS A1302 and OXY A1304

Chain	Residue
A	ILE54
A	ALA56
A	THR57
A	ASP58
A	PHE159
A	LEU170
A	ARG176
A	SER226
A	VAL227
A	GLN228
A	ASN254
A	HIS256
A	GLY286
A	ILE288
A	MUA1305

---

Functional Information from PROSITE/UniProt

site_id	PS00366
Number of Residues	28
Details	URICASE Uricase signature. LtVLKSTnSqFwgFlrdeYttLketwdR

Chain	Residue	Details
A	LEU149-ARG176

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Active site: {"description":"Charge relay system","evidences":[{"source":"PubMed","id":"24466188","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4N3M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N9M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N9S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N9V","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9360612","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1R4S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1R51","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1WS2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FUB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FXL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IBA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ICQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PES","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZKA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZKB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BK8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CKS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CKU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3F2M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GKO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3LBG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3LD4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3P9F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PJK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N9S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N9V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OP6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OP9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FRC","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9360612","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1R4S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3LBG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3LD4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N9S","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9360612","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1R4S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1R51","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1WS3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XT4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XY3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FUB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IBA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ICQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PES","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZKA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZKB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BK8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CKS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CKU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3F2M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GKO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L8W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3P9F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PJK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N9V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OP6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OP9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FRC","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9360612","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1R4S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1R51","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1WRR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1WS2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1WS3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XT4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XXJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XY3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FUB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IBA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ICQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PES","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZKA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZKB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BK8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CKS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CKU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3F2M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GKO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L8W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3LBG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3P9F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PJK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N9V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OP6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OP9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FRC","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9360612","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1R4S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1R51","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1WRR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XT4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XXJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XY3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FUB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IBA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ICQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PES","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZKA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZKB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BK8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CKS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CKU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3F2M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GKO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L8W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3P9F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PJK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N9V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OP6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OP9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FRC","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9360612","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1R4S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1R51","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1WRR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1WS2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XT4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XXJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XY3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FUB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IBA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ICQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PES","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZKA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZKB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BK8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CKS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CKU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3F2M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GKO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L8W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3LBG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3LD4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3P9F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PJK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N9S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N9V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OP6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OP9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FRC","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PDB","id":"4CW2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW6","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	5
Details	M-CSA 118

Chain	Residue	Details
A	ARG14	hydrogen bond donor, proton acceptor, proton donor, proton relay
A	LYS61	electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay
A	THR180	electrostatic stabiliser
A	TYR232	electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor
A	ILE260	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay

---