Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004517 | molecular_function | nitric-oxide synthase activity |
| A | 0006809 | biological_process | nitric oxide biosynthetic process |
| B | 0004517 | molecular_function | nitric-oxide synthase activity |
| B | 0006809 | biological_process | nitric oxide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE HEM A 500 |
| Chain | Residue |
| A | TRP180 |
| A | PHE475 |
| A | TYR477 |
| A | ARG700 |
| A | WSD800 |
| A | HOH2095 |
| A | HOH2147 |
| A | HOH2150 |
| A | HOH2151 |
| A | HOH2152 |
| A | ARG185 |
| A | CYS186 |
| A | SER228 |
| A | PHE355 |
| A | SER356 |
| A | TRP358 |
| A | GLU363 |
| A | TRP449 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE ARG A 700 |
| Chain | Residue |
| A | GLN249 |
| A | ARG252 |
| A | TYR333 |
| A | TRP358 |
| A | TYR359 |
| A | GLU363 |
| A | ASN368 |
| A | HEM500 |
| A | HOH2091 |
| A | HOH2100 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE WSD A 800 |
| Chain | Residue |
| A | ARG367 |
| A | ALA448 |
| A | TRP449 |
| A | HEM500 |
| A | HOH2132 |
| A | HOH2152 |
| B | TRP76 |
| B | TRP447 |
| B | PHE462 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT A 860 |
| Chain | Residue |
| A | TRP358 |
| A | VAL420 |
| A | SER428 |
| site_id | AC5 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE HEM B 500 |
| Chain | Residue |
| B | TRP180 |
| B | ARG185 |
| B | CYS186 |
| B | PHE355 |
| B | SER356 |
| B | TRP358 |
| B | GLU363 |
| B | TRP449 |
| B | TYR477 |
| B | ARG700 |
| B | WSD800 |
| B | HOH2121 |
| B | HOH2123 |
| B | HOH2124 |
| B | HOH2125 |
| B | HOH2126 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE ARG B 700 |
| Chain | Residue |
| B | GLN249 |
| B | TYR333 |
| B | VAL338 |
| B | TRP358 |
| B | TYR359 |
| B | GLU363 |
| B | ASN368 |
| B | HEM500 |
| B | HOH2090 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE WSD B 800 |
| Chain | Residue |
| A | TRP447 |
| A | PHE462 |
| B | ARG367 |
| B | ALA448 |
| B | TRP449 |
| B | HEM500 |
| B | HOH2114 |
| B | HOH2126 |
| B | HOH2127 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT B 860 |
| Chain | Residue |
| B | TRP358 |
| B | VAL420 |
| B | SER428 |
| B | HOH2030 |
| B | HOH2104 |
Functional Information from PROSITE/UniProt
| site_id | PS60001 |
| Number of Residues | 8 |
| Details | NOS Nitric oxide synthase (NOS) signature. RCVGRIqW |
| Chain | Residue | Details |
| A | ARG185-TRP192 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"source":"UniProtKB","id":"P29474","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P29474","evidenceCode":"ECO:0000250"}]} |
