Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004517 | molecular_function | nitric-oxide synthase activity |
| A | 0006809 | biological_process | nitric oxide biosynthetic process |
| B | 0004517 | molecular_function | nitric-oxide synthase activity |
| B | 0006809 | biological_process | nitric oxide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE HEM A 1717 |
| Chain | Residue |
| A | TRP409 |
| A | H4B1718 |
| A | 7S71719 |
| A | HOH2137 |
| A | HOH2138 |
| A | HOH2139 |
| A | ARG414 |
| A | CYS415 |
| A | VAL416 |
| A | SER457 |
| A | PHE584 |
| A | SER585 |
| A | TRP587 |
| A | GLU592 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE H4B A 1718 |
| Chain | Residue |
| A | SER334 |
| A | ARG596 |
| A | VAL677 |
| A | TRP678 |
| A | HEM1717 |
| A | HOH2037 |
| A | HOH2104 |
| A | HOH2124 |
| A | HOH2138 |
| B | TRP676 |
| B | PHE691 |
| B | HIS692 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 7S7 A 1719 |
| Chain | Residue |
| A | PRO565 |
| A | VAL567 |
| A | PHE584 |
| A | TRP587 |
| A | GLU592 |
| A | TYR706 |
| A | HEM1717 |
| A | HOH2100 |
| A | HOH2140 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE ACT A 1720 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE HEM B 1719 |
| Chain | Residue |
| B | TRP409 |
| B | ARG414 |
| B | CYS415 |
| B | VAL416 |
| B | SER457 |
| B | PHE584 |
| B | SER585 |
| B | TRP587 |
| B | GLU592 |
| B | TRP678 |
| B | H4B1720 |
| B | 7S71721 |
| B | HOH2174 |
| B | HOH2175 |
| B | HOH2176 |
| site_id | AC6 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE H4B B 1720 |
| Chain | Residue |
| A | TRP676 |
| A | PHE691 |
| A | HIS692 |
| A | GLN693 |
| A | GLU694 |
| A | HOH2131 |
| B | SER334 |
| B | ARG596 |
| B | VAL677 |
| B | TRP678 |
| B | HEM1719 |
| B | HOH2010 |
| B | HOH2142 |
| B | HOH2166 |
| B | HOH2176 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 7S7 B 1721 |
| Chain | Residue |
| A | TRP306 |
| B | PRO565 |
| B | VAL567 |
| B | PHE584 |
| B | GLY586 |
| B | TRP587 |
| B | GLU592 |
| B | HEM1719 |
| B | HOH2092 |
| B | HOH2140 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT B 1722 |
| Chain | Residue |
| B | GLY417 |
| B | TRP587 |
| B | HOH2040 |
| B | HOH2158 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1721 |
| Chain | Residue |
| A | CYS326 |
| A | CYS331 |
| B | CYS326 |
| B | CYS331 |
Functional Information from PROSITE/UniProt
| site_id | PS60001 |
| Number of Residues | 8 |
| Details | NOS Nitric oxide synthase (NOS) signature. RCVGRIqW |
| Chain | Residue | Details |
| A | ARG414-TRP421 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P29475","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"source":"UniProtKB","id":"P29475","evidenceCode":"ECO:0000250"}]} |
