4CSH
Native structure of the lytic CHAPK domain of the endolysin LysK from Staphylococcus aureus bacteriophage K
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 1166 |
| Chain | Residue |
| A | ARG11 |
| A | SER22 |
| A | PRO23 |
| A | ASP60 |
| A | TRP64 |
| A | ASN68 |
| A | HOH2102 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 1167 |
| Chain | Residue |
| A | TYR49 |
| A | HIS51 |
| A | ASP56 |
| A | HOH2085 |
| A | ASP45 |
| A | ASP47 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 1166 |
| Chain | Residue |
| B | ASP45 |
| B | ASP47 |
| B | TYR49 |
| B | HIS51 |
| B | ASP56 |
| B | HOH2088 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 1166 |
| Chain | Residue |
| C | ASP45 |
| C | ASP47 |
| C | TYR49 |
| C | HIS51 |
| C | ASP56 |
| C | HOH2067 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA D 1166 |
| Chain | Residue |
| D | ASP45 |
| D | ASP47 |
| D | TYR49 |
| D | HIS51 |
| D | ASP56 |
| D | HOH2059 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MES A 1168 |
| Chain | Residue |
| A | GLN53 |
| A | CYS54 |
| A | GLN55 |
| A | ASN75 |
| A | ALA76 |
| A | ZN1170 |
| A | HOH2112 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MES B 1167 |
| Chain | Residue |
| B | GLN53 |
| B | CYS54 |
| B | GLN55 |
| B | ASN75 |
| B | ALA76 |
| B | ZN1169 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE MES D 1167 |
| Chain | Residue |
| D | TYR50 |
| D | GLN53 |
| D | CYS54 |
| D | GLN55 |
| D | ASN75 |
| D | ALA76 |
| D | TRP115 |
| D | ZN1169 |
| D | HOH2075 |
| D | HOH2092 |
| D | HOH2093 |
| site_id | AC9 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE MES C 1167 |
| Chain | Residue |
| C | TYR50 |
| C | GLN53 |
| C | CYS54 |
| C | GLN55 |
| C | ASN75 |
| C | ALA76 |
| C | TRP115 |
| C | ZN1169 |
| C | HOH2080 |
| C | HOH2100 |
| C | HOH2101 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 1169 |
| Chain | Residue |
| A | ASN93 |
| A | LYS94 |
| A | THR97 |
| A | TYR152 |
| A | HOH2143 |
| A | HOH2145 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 1168 |
| Chain | Residue |
| B | ASN93 |
| B | LYS94 |
| B | THR97 |
| B | TYR152 |
| B | HOH2147 |
| B | HOH2150 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA C 1168 |
| Chain | Residue |
| C | ASN93 |
| C | LYS94 |
| C | THR97 |
| C | TYR152 |
| C | HOH2121 |
| C | HOH2123 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA D 1168 |
| Chain | Residue |
| D | ASN93 |
| D | LYS94 |
| D | THR97 |
| D | HOH2114 |
| D | HOH2115 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A 1170 |
| Chain | Residue |
| A | CYS54 |
| A | GLY116 |
| A | MES1168 |
| A | HOH2094 |
| A | HOH2097 |
| A | HOH2212 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN C 1169 |
| Chain | Residue |
| C | HOH2079 |
| C | HOH2172 |
| C | CYS54 |
| C | GLY116 |
| C | MES1167 |
| C | HOH2075 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 1169 |
| Chain | Residue |
| B | CYS54 |
| B | GLY116 |
| B | MES1167 |
| B | HOH2098 |
| B | HOH2100 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN D 1169 |
| Chain | Residue |
| D | CYS54 |
| D | GLY116 |
| D | MES1167 |
| D | HOH2071 |
| D | HOH2074 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 524 |
| Details | Domain: {"description":"Peptidase C51","evidences":[{"source":"PROSITE-ProRule","id":"PRU00048","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Active site: {"description":"For endopeptidase activity","evidences":[{"source":"PubMed","id":"25064136","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Active site: {"description":"For endopeptidase activity","evidences":[{"source":"PubMed","id":"25064136","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25064136","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4CSH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CT3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
