4CS6
Crystal structure of AadA - an aminoglycoside adenyltransferase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005524 | molecular_function | ATP binding |
| A | 0009012 | molecular_function | aminoglycoside 3''-adenylyltransferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0046677 | biological_process | response to antibiotic |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070566 | molecular_function | adenylyltransferase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton acceptor => ECO:0000305|PubMed:26527143, ECO:0000305|PubMed:29871922 |
| Chain | Residue | Details |
| A | GLU87 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:29871922, ECO:0007744|PDB:5G4A, ECO:0007744|PDB:5LPA, ECO:0007744|PDB:5LUH, ECO:0007744|PDB:6FZB |
| Chain | Residue | Details |
| A | SER36 | |
| A | SER46 | |
| A | ASP47 | |
| A | ASP49 | |
| A | GLU87 | |
| A | ASP130 | |
| A | LYS205 | |
| A | TYR231 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:29871922, ECO:0007744|PDB:5LPA, ECO:0007744|PDB:5LUH, ECO:0007744|PDB:6FZB |
| Chain | Residue | Details |
| A | TRP173 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:29871922, ECO:0007744|PDB:5LPA, ECO:0007744|PDB:5LUH |
| Chain | Residue | Details |
| A | HIS185 |
