4CRM
Cryo-EM of a pre-recycling complex with eRF1 and ABCE1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| P | 0000054 | biological_process | ribosomal subunit export from nucleus |
| P | 0000166 | molecular_function | nucleotide binding |
| P | 0003743 | molecular_function | translation initiation factor activity |
| P | 0005506 | molecular_function | iron ion binding |
| P | 0005515 | molecular_function | protein binding |
| P | 0005524 | molecular_function | ATP binding |
| P | 0005634 | cellular_component | nucleus |
| P | 0005737 | cellular_component | cytoplasm |
| P | 0005829 | cellular_component | cytosol |
| P | 0005852 | cellular_component | eukaryotic translation initiation factor 3 complex |
| P | 0006364 | biological_process | rRNA processing |
| P | 0006412 | biological_process | translation |
| P | 0006413 | biological_process | translational initiation |
| P | 0006415 | biological_process | translational termination |
| P | 0016887 | molecular_function | ATP hydrolysis activity |
| P | 0032790 | biological_process | ribosome disassembly |
| P | 0042254 | biological_process | ribosome biogenesis |
| P | 0042273 | biological_process | ribosomal large subunit biogenesis |
| P | 0043024 | molecular_function | ribosomal small subunit binding |
| P | 0045727 | biological_process | positive regulation of translation |
| P | 0060255 | biological_process | regulation of macromolecule metabolic process |
| X | 0003747 | molecular_function | translation release factor activity |
| X | 0006415 | biological_process | translational termination |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE ATP P 1609 |
| Chain | Residue |
| P | HOH1903 |
| P | THR118 |
| P | SER299 |
| P | MG1613 |
| P | TYR87 |
| P | PHE92 |
| P | ASN112 |
| P | GLY113 |
| P | ILE114 |
| P | GLY115 |
| P | LYS116 |
| P | SER117 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SF4 P 1610 |
| Chain | Residue |
| P | CYS29 |
| P | CYS38 |
| P | ILE50 |
| P | CYS55 |
| P | CYS58 |
| P | GLY59 |
| P | CYS61 |
| P | ILE72 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SF4 P 1611 |
| Chain | Residue |
| P | CYS16 |
| P | LYS17 |
| P | PRO18 |
| P | CYS21 |
| P | ARG22 |
| P | GLU24 |
| P | CYS25 |
| P | CYS65 |
| P | PRO66 |
| P | PHE67 |
| P | ALA69 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE ADP P 1612 |
| Chain | Residue |
| P | ARG217 |
| P | GLN363 |
| P | PHE366 |
| P | GLU386 |
| P | ASN387 |
| P | GLY388 |
| P | THR389 |
| P | GLY390 |
| P | LYS391 |
| P | THR392 |
| P | THR393 |
| P | SER546 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG P 1613 |
| Chain | Residue |
| P | SER117 |
| P | GLN171 |
| P | ATP1609 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: N5-methylglutamine => ECO:0000269|PubMed:15509572, ECO:0000269|PubMed:16321977 |
| Chain | Residue | Details |
| X | GLN182 | |
| P | GLY385 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198 |
| Chain | Residue | Details |
| X | SER421 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047 |
| Chain | Residue | Details |
| X | LYS331 |
