Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003848 | molecular_function | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity |
| A | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE APC A 1159 |
| Chain | Residue |
| A | LEU71 |
| A | SER112 |
| A | HIS115 |
| A | ARG117 |
| A | ARG121 |
| A | MG1160 |
| A | MG1161 |
| A | HOH2033 |
| A | HOH2034 |
| A | HOH2039 |
| A | HOH2040 |
| A | ARG83 |
| A | HOH2041 |
| A | HOH2045 |
| A | HOH2047 |
| A | HOH2083 |
| A | ARG88 |
| A | ARG92 |
| A | ASP95 |
| A | ASP97 |
| A | ILE98 |
| A | LYS110 |
| A | LEU111 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 1160 |
| Chain | Residue |
| A | ASP95 |
| A | ASP97 |
| A | APC1159 |
| A | MG1161 |
| A | HOH2034 |
| A | HOH2047 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 1161 |
| Chain | Residue |
| A | ASP95 |
| A | ASP97 |
| A | APC1159 |
| A | MG1160 |
| A | HOH2045 |
| A | HOH2046 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NO3 A 1162 |
| Chain | Residue |
| A | ILE12 |
| A | ARG83 |
| A | ILE84 |
| A | ARG85 |
| A | ARG92 |
| A | THR93 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE YH5 A 1163 |
| Chain | Residue |
| A | THR43 |
| A | ALA44 |
| A | PRO45 |
| A | VAL46 |
| A | GLY47 |
| A | PHE54 |
| A | ASN56 |
| A | GLU104 |
| A | MET105 |
| A | ILE106 |
| A | ARG121 |
| A | PHE123 |
| A | HOH2044 |
| A | HOH2045 |
Functional Information from PROSITE/UniProt
| site_id | PS00794 |
| Number of Residues | 12 |
| Details | HPPK 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. RwGPRtlDVDIL |
| Chain | Residue | Details |
| A | ARG88-LEU99 | |
4CRJ
