Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE MVN A 1476 |
| Chain | Residue |
| A | ASP189 |
| A | VAL227 |
| A | TYR228 |
| A | ALA190 |
| A | SER195 |
| A | SER214 |
| A | TRP215 |
| A | GLY216 |
| A | GLY218 |
| A | CYS219 |
| A | GLY226 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1477 |
| Chain | Residue |
| A | THR20 |
| A | ALA21 |
| A | GLN48 |
| A | GLN86 |
| A | HOH2007 |
| A | HOH2223 |
| A | HOH2285 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1478 |
| Chain | Residue |
| A | LYS202 |
| A | TRP203 |
| A | HOH2023 |
| A | HOH2024 |
| A | HOH2257 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1479 |
| Chain | Residue |
| A | LYS127 |
| A | LYS127 |
| A | LYS127 |
| A | ARG130 |
| A | ARG130 |
| A | ARG130 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1480 |
| Chain | Residue |
| A | HIS91 |
| A | TRP237 |
| A | HOH2161 |
| A | HOH2168 |
| A | HOH2247 |
| A | HOH2276 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1481 |
| Chain | Residue |
| A | HIS57 |
| A | LYS192 |
| A | GLY193 |
| A | SER195 |
| A | HOH2071 |
| A | HOH2087 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1482 |
| Chain | Residue |
| A | ASN113 |
| A | TYR143 |
| A | ARG147 |
| A | LYS149 |
| A | LYS192 |
| A | HOH2189 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1483 |
| Chain | Residue |
| A | TYR184 |
| A | ARG185 |
| A | GLU186 |
| A | HOH2250 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1484 |
| Chain | Residue |
| A | PHE83 |
| A | ASN113 |
| A | GLN118 |
| A | ARG147 |
| A | HOH2139 |
| A | HOH2190 |
| A | HOH2192 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
| Chain | Residue | Details |
| A | LEU53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DAckGDSGGPLS |
| Chain | Residue | Details |
| A | ASP189-SER198 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | HIS57 | |
| A | ASP102 | |
| A | SER195 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | LYS170 | |
| Chain | Residue | Details |
| A | ASN73 | |
| Chain | Residue | Details |
| A | ASN113 | |
