4COM
Crystal structure of the anaerobic ribonucleotide reductase from Thermotoga maritima with MES in the active site
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004748 | molecular_function | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
| A | 0006260 | biological_process | DNA replication |
| A | 0008998 | molecular_function | ribonucleoside-triphosphate reductase (thioredoxin) activity |
| A | 0009265 | biological_process | 2'-deoxyribonucleotide biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0031250 | cellular_component | anaerobic ribonucleoside-triphosphate reductase complex |
| B | 0004748 | molecular_function | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
| B | 0006260 | biological_process | DNA replication |
| B | 0008998 | molecular_function | ribonucleoside-triphosphate reductase (thioredoxin) activity |
| B | 0009265 | biological_process | 2'-deoxyribonucleotide biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0031250 | cellular_component | anaerobic ribonucleoside-triphosphate reductase complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 700 |
| Chain | Residue |
| A | CYS594 |
| A | HIS598 |
| A | CYS605 |
| A | CYS608 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 652 |
| Chain | Residue |
| B | CYS594 |
| B | HIS598 |
| B | CYS605 |
| B | CYS608 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MES A 1634 |
| Chain | Residue |
| A | TYR124 |
| A | TYR227 |
| A | PRO498 |
| A | ALA499 |
| A | GLU500 |
| A | HOH2068 |
| A | HOH2329 |
| A | HIS114 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE MES B 1631 |
| Chain | Residue |
| B | HIS114 |
| B | TYR124 |
| B | TYR227 |
| B | VAL497 |
| B | PRO498 |
| B | ALA499 |
| B | GLU500 |
| B | HOH2066 |
| B | HOH2075 |
| B | HOH2107 |
| B | HOH2275 |
| B | HOH2278 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE 1PE B 1632 |
| Chain | Residue |
| B | ARG221 |
| B | HOH2128 |
| B | HOH2328 |
