4COI
Crystal structure of the anaerobic ribonucleotide reductase from Thermotoga maritima with glycerol in the active site
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004748 | molecular_function | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
| A | 0006260 | biological_process | DNA replication |
| A | 0008998 | molecular_function | ribonucleoside-triphosphate reductase (thioredoxin) activity |
| A | 0009265 | biological_process | 2'-deoxyribonucleotide biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0031250 | cellular_component | anaerobic ribonucleoside-triphosphate reductase complex |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004748 | molecular_function | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
| B | 0006260 | biological_process | DNA replication |
| B | 0008998 | molecular_function | ribonucleoside-triphosphate reductase (thioredoxin) activity |
| B | 0009265 | biological_process | 2'-deoxyribonucleotide biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0031250 | cellular_component | anaerobic ribonucleoside-triphosphate reductase complex |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 652 |
| Chain | Residue |
| A | CYS594 |
| A | HIS598 |
| A | CYS605 |
| A | CYS608 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 652 |
| Chain | Residue |
| B | CYS594 |
| B | HIS598 |
| B | CYS605 |
| B | CYS608 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 1641 |
| Chain | Residue |
| B | HIS114 |
| B | ASP115 |
| B | GLU500 |
| B | LYS501 |
| B | ALA502 |
| B | HOH2033 |
| B | TYR112 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 1640 |
| Chain | Residue |
| A | TYR112 |
| A | HIS114 |
| A | ASP115 |
| A | ALA499 |
| A | GLU500 |
| A | LYS501 |
| A | ALA502 |
| A | HOH2053 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 1641 |
| Chain | Residue |
| A | ARG395 |
| A | ASP475 |
| A | THR476 |
| A | GLU479 |
| B | ASP471 |
| B | ASP475 |
| B | LYS549 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 1642 |
| Chain | Residue |
| B | PRO606 |
| B | VAL607 |
| B | HOH2195 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 1642 |
| Chain | Residue |
| A | GLN157 |
| A | HOH2082 |
| A | HOH2272 |
| B | GLN157 |
