4CO9
Crystal structure of kynurenine formamidase from Bacillus anthracis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004061 | molecular_function | arylformamidase activity |
| A | 0004328 | molecular_function | formamidase activity |
| A | 0006569 | biological_process | tryptophan catabolic process |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0019441 | biological_process | tryptophan catabolic process to kynurenine |
| A | 0043420 | biological_process | anthranilate metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004061 | molecular_function | arylformamidase activity |
| B | 0004328 | molecular_function | formamidase activity |
| B | 0006569 | biological_process | tryptophan catabolic process |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0019441 | biological_process | tryptophan catabolic process to kynurenine |
| B | 0043420 | biological_process | anthranilate metabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0004061 | molecular_function | arylformamidase activity |
| C | 0004328 | molecular_function | formamidase activity |
| C | 0006569 | biological_process | tryptophan catabolic process |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0019441 | biological_process | tryptophan catabolic process to kynurenine |
| C | 0043420 | biological_process | anthranilate metabolic process |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0004061 | molecular_function | arylformamidase activity |
| D | 0004328 | molecular_function | formamidase activity |
| D | 0006569 | biological_process | tryptophan catabolic process |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0019441 | biological_process | tryptophan catabolic process to kynurenine |
| D | 0043420 | biological_process | anthranilate metabolic process |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A 401 |
| Chain | Residue |
| A | ASP56 |
| A | HIS161 |
| A | GLU173 |
| A | ZN402 |
| A | HOH2108 |
| A | HOH2238 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ZN A 402 |
| Chain | Residue |
| A | GLU173 |
| A | ZN401 |
| A | HOH2044 |
| A | HOH2108 |
| A | HIS50 |
| A | HIS54 |
| A | ASP56 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN B 401 |
| Chain | Residue |
| B | ASP56 |
| B | HIS161 |
| B | GLU173 |
| B | ZN402 |
| B | HOH2073 |
| B | HOH2147 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ZN B 402 |
| Chain | Residue |
| B | HIS50 |
| B | HIS54 |
| B | ASP56 |
| B | GLU173 |
| B | ZN401 |
| B | HOH2037 |
| B | HOH2073 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN C 401 |
| Chain | Residue |
| C | ASP56 |
| C | HIS161 |
| C | GLU173 |
| C | ZN402 |
| C | HOH2102 |
| C | HOH2201 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ZN C 402 |
| Chain | Residue |
| C | HIS50 |
| C | HIS54 |
| C | ASP56 |
| C | GLU173 |
| C | ZN401 |
| C | HOH2048 |
| C | HOH2102 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN D 401 |
| Chain | Residue |
| D | ASP56 |
| D | HIS161 |
| D | GLU173 |
| D | ZN402 |
| D | HOH2075 |
| D | HOH2163 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ZN D 402 |
| Chain | Residue |
| D | HIS50 |
| D | HIS54 |
| D | ASP56 |
| D | GLU173 |
| D | ZN401 |
| D | HOH2036 |
| D | HOH2075 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 1214 |
| Chain | Residue |
| A | HOH2119 |
| A | HOH2123 |
| A | HOH2124 |
| A | HOH2291 |
| A | HOH2292 |
| A | HOH2293 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 1215 |
| Chain | Residue |
| A | HOH2269 |
| A | HOH2294 |
| A | HOH2295 |
| A | HOH2296 |
| D | HOH2085 |
| D | HOH2087 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG C 1211 |
| Chain | Residue |
| C | HOH2108 |
| C | HOH2109 |
| C | HOH2118 |
| C | HOH2238 |
| C | HOH2239 |
| C | HOH2240 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG C 1210 |
| Chain | Residue |
| C | GLY38 |
| C | HOH2086 |
| C | HOH2087 |
| C | HOH2088 |
| C | HOH2089 |
| C | HOH2237 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 1210 |
| Chain | Residue |
| A | GLY38 |
| A | HOH2088 |
| A | HOH2089 |
| A | HOH2090 |
| A | HOH2091 |
| A | HOH2288 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DIO A 1211 |
| Chain | Residue |
| A | TRP6 |
| A | GLU186 |
| A | ARG207 |
| A | HOH2273 |
| B | TRP6 |
| B | GLU186 |
| B | ARG207 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE DIO D 1210 |
| Chain | Residue |
| C | ARG207 |
| D | TRP6 |
| D | GLU186 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GXT A 1212 |
| Chain | Residue |
| A | GLY183 |
| A | ASP184 |
| A | HOH2270 |
| A | HOH2289 |
| D | ASP64 |
| site_id | BC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GXT A 1213 |
| Chain | Residue |
| A | GLU102 |
| A | HOH2194 |
| site_id | BC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GXT D 1211 |
| Chain | Residue |
| D | PRO12 |
| D | HOH2020 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_01969, ECO:0000305|PubMed:24942958 |
| Chain | Residue | Details |
| A | HIS60 | |
| B | HIS60 | |
| C | HIS60 | |
| D | HIS60 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:24942958, ECO:0007744|PDB:4CZ1 |
| Chain | Residue | Details |
| A | TRP20 | |
| B | TRP20 | |
| C | TRP20 | |
| D | TRP20 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 20 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01969, ECO:0000269|PubMed:24942958, ECO:0007744|PDB:4CO9, ECO:0007744|PDB:4CZ1 |
| Chain | Residue | Details |
| A | HIS50 | |
| B | GLU173 | |
| C | HIS50 | |
| C | HIS54 | |
| C | ASP56 | |
| C | HIS161 | |
| C | GLU173 | |
| D | HIS50 | |
| D | HIS54 | |
| D | ASP56 | |
| D | HIS161 | |
| A | HIS54 | |
| D | GLU173 | |
| A | ASP56 | |
| A | HIS161 | |
| A | GLU173 | |
| B | HIS50 | |
| B | HIS54 | |
| B | ASP56 | |
| B | HIS161 |
