Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000166 | molecular_function | nucleotide binding |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0047040 | molecular_function | pteridine reductase activity |
B | 0000166 | molecular_function | nucleotide binding |
B | 0016491 | molecular_function | oxidoreductase activity |
B | 0047040 | molecular_function | pteridine reductase activity |
C | 0000166 | molecular_function | nucleotide binding |
C | 0016491 | molecular_function | oxidoreductase activity |
C | 0047040 | molecular_function | pteridine reductase activity |
D | 0000166 | molecular_function | nucleotide binding |
D | 0016491 | molecular_function | oxidoreductase activity |
D | 0047040 | molecular_function | pteridine reductase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 34 |
Details | BINDING SITE FOR RESIDUE NAP A 1269 |
Chain | Residue |
A | ARG14 |
A | THR64 |
A | ASN93 |
A | ALA94 |
A | SER95 |
A | THR126 |
A | LEU159 |
A | CYS160 |
A | TYR174 |
A | LYS178 |
A | PRO204 |
A | ILE15 |
A | GLY205 |
A | SER207 |
A | LEU208 |
A | IZ91270 |
A | HOH2008 |
A | HOH2009 |
A | HOH2010 |
A | HOH2013 |
A | HOH2017 |
A | HOH2049 |
A | TYR34 |
A | HOH2054 |
A | HOH2154 |
A | HOH2157 |
A | HOH2298 |
A | HOH2300 |
A | HIS35 |
A | ASN36 |
A | SER37 |
A | ALA61 |
A | ASP62 |
A | LEU63 |
site_id | AC2 |
Number of Residues | 32 |
Details | BINDING SITE FOR RESIDUE NAP B 1269 |
Chain | Residue |
B | ARG14 |
B | ILE15 |
B | TYR34 |
B | HIS35 |
B | ASN36 |
B | SER37 |
B | ALA61 |
B | ASP62 |
B | LEU63 |
B | THR64 |
B | ASN93 |
B | ALA94 |
B | SER95 |
B | THR126 |
B | LEU159 |
B | CYS160 |
B | TYR174 |
B | LYS178 |
B | PRO204 |
B | GLY205 |
B | SER207 |
B | LEU208 |
B | IZ91270 |
B | HOH2008 |
B | HOH2009 |
B | HOH2010 |
B | HOH2023 |
B | HOH2060 |
B | HOH2068 |
B | HOH2073 |
B | HOH2156 |
B | HOH2289 |
site_id | AC3 |
Number of Residues | 33 |
Details | BINDING SITE FOR RESIDUE NAP C 1269 |
Chain | Residue |
C | ARG14 |
C | ILE15 |
C | TYR34 |
C | HIS35 |
C | ASN36 |
C | SER37 |
C | ALA61 |
C | ASP62 |
C | LEU63 |
C | THR64 |
C | ASN93 |
C | ALA94 |
C | SER95 |
C | THR126 |
C | LEU159 |
C | CYS160 |
C | TYR174 |
C | LYS178 |
C | PRO204 |
C | GLY205 |
C | SER207 |
C | LEU208 |
C | IZ91270 |
C | HOH2009 |
C | HOH2010 |
C | HOH2011 |
C | HOH2019 |
C | HOH2047 |
C | HOH2053 |
C | HOH2131 |
C | HOH2134 |
C | HOH2238 |
C | HOH2240 |
site_id | AC4 |
Number of Residues | 32 |
Details | BINDING SITE FOR RESIDUE NAP D 1269 |
Chain | Residue |
D | ARG14 |
D | ILE15 |
D | TYR34 |
D | HIS35 |
D | ASN36 |
D | SER37 |
D | ALA61 |
D | ASP62 |
D | LEU63 |
D | THR64 |
D | ASN93 |
D | ALA94 |
D | SER95 |
D | THR126 |
D | LEU159 |
D | CYS160 |
D | TYR174 |
D | LYS178 |
D | PRO204 |
D | GLY205 |
D | SER207 |
D | LEU208 |
D | IZ91270 |
D | HOH2005 |
D | HOH2006 |
D | HOH2007 |
D | HOH2018 |
D | HOH2045 |
D | HOH2051 |
D | HOH2114 |
D | HOH2204 |
D | HOH2205 |
site_id | AC5 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE IZ9 A 1270 |
Chain | Residue |
A | ARG14 |
A | SER95 |
A | PHE97 |
A | ASP161 |
A | MET163 |
A | CSX168 |
A | TYR174 |
A | GLY205 |
A | PRO210 |
A | TRP221 |
A | NAP1269 |
A | DTT1272 |
A | HOH2017 |
D | HIS267 |
site_id | AC6 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE IZ9 B 1270 |
Chain | Residue |
B | ARG14 |
B | SER95 |
B | PHE97 |
B | ASP161 |
B | MET163 |
B | GLN166 |
B | CYS168 |
B | TYR174 |
B | GLY205 |
B | PRO210 |
B | TRP221 |
B | NAP1269 |
B | DTT1271 |
B | HOH2023 |
B | HOH2195 |
C | HIS267 |
site_id | AC7 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE IZ9 C 1270 |
Chain | Residue |
B | HIS267 |
C | ARG14 |
C | SER95 |
C | PHE97 |
C | ASP161 |
C | MET163 |
C | GLN166 |
C | CSX168 |
C | TYR174 |
C | PRO210 |
C | TRP221 |
C | NAP1269 |
C | GOL1272 |
C | HOH2019 |
C | HOH2163 |
C | HOH2171 |
site_id | AC8 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE IZ9 D 1270 |
Chain | Residue |
A | HIS267 |
D | ARG14 |
D | SER95 |
D | PHE97 |
D | ASP161 |
D | MET163 |
D | GLN166 |
D | CSX168 |
D | TYR174 |
D | PRO210 |
D | TRP221 |
D | NAP1269 |
D | GOL1271 |
D | HOH2018 |
D | HOH2149 |
site_id | AC9 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE ACT A 1271 |
Chain | Residue |
A | LYS13 |
A | ARG14 |
A | ARG17 |
A | HOH2015 |
A | HOH2301 |
site_id | BC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE ACT C 1271 |
Chain | Residue |
B | TYR34 |
B | VAL58 |
C | VAL57 |
C | VAL58 |
C | HOH2081 |
site_id | BC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE DTT A 1272 |
Chain | Residue |
A | PHE97 |
A | CSX168 |
A | LEU209 |
A | IZ91270 |
A | HOH2302 |
site_id | BC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE DTT B 1271 |
Chain | Residue |
B | PHE97 |
B | CYS168 |
B | IZ91270 |
B | HOH2290 |
site_id | BC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE GOL C 1272 |
Chain | Residue |
C | CSX168 |
C | MET213 |
C | TRP221 |
C | IZ91270 |
C | HOH2242 |
site_id | BC5 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GOL D 1271 |
Chain | Residue |
D | PHE97 |
D | CSX168 |
D | VAL206 |
D | MET213 |
D | TRP221 |
D | IZ91270 |
D | HOH2054 |
Functional Information from PROSITE/UniProt
site_id | PS00061 |
Number of Residues | 29 |
Details | ADH_SHORT Short-chain dehydrogenases/reductases family signature. DamvdqpcmaFslYNMGKHALvGLTqSAA |
Chain | Residue | Details |
A | ASP161-ALA189 | |
B | ASP161-ALA189 | |