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4CLF

Crystal structure of human soluble Adenylyl Cyclase (Apo form)

Functional Information from GO Data
ChainGOidnamespacecontents
A0009190biological_processcyclic nucleotide biosynthetic process
A0035556biological_processintracellular signal transduction
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ACT A 1469
ChainResidue
ALYS95
ALEU166
AVAL167
AMET337

site_idAC2
Number of Residues9
DetailsBINDING SITE FOR RESIDUE GOL A 1470
ChainResidue
ALEU261
ASER264
AHOH2188
AHOH2286
AILE24
AVAL25
AGLY27
AHIS28
APHE29

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00099
ChainResidueDetails
AASP47
AILE48
AASP99

site_idSWS_FT_FI2
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:24567411, ECO:0000269|PubMed:24616449, ECO:0007744|PDB:4CLL, ECO:0007744|PDB:4OYZ
ChainResidueDetails
ALYS95
AVAL167
AARG176
AMET337

site_idSWS_FT_FI3
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:25040695, ECO:0000305|PubMed:24567411, ECO:0000305|PubMed:24616449, ECO:0007744|PDB:4USW
ChainResidueDetails
ALYS144
AVAL406

site_idSWS_FT_FI4
Number of Residues1
DetailsBINDING: BINDING => ECO:0000305|PubMed:24567411, ECO:0000305|PubMed:24616449, ECO:0000305|PubMed:25040695
ChainResidueDetails
AASN412

226707

PDB entries from 2024-10-30

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