4CGK

Crystal structure of the essential protein PcsB from Streptococcus pneumoniae

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 1393

Chain	Residue
A	LEU257
A	THR258

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 1394

Chain	Residue
A	PHE385
A	VAL386
A	CL1399
A	HOH2202
A	HOH2252

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG B 1393

Chain	Residue
B	HIS372
B	HOH2186
B	THR368
B	GLY370

---

site_id	AC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE PG4 B 1394

Chain	Residue
B	GLU291
B	CYS292
B	GLY342
B	HIS343
B	ASN362
B	ALA364
B	SER382
B	GLU383
B	HOH2179
B	HOH2187

---

site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 1395

Chain	Residue
A	HIS372

---

site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 1396

Chain	Residue
A	ARG367

---

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 1397

Chain	Residue
A	ASN256
B	LEU299

---

site_id	AC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 1398

Chain	Residue
A	ALA364

---

site_id	AC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 1400

Chain	Residue
A	CL1401

---

site_id	BC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL B 1395

Chain	Residue
B	ILE289

---

site_id	BC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 1401

Chain	Residue
A	CL1400
B	HOH2118

---

site_id	BC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL A 1399

Chain	Residue
A	THR379
A	GLY384
A	PHE385
A	EDO1394
B	GLY384
B	PHE385

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	246
Details	Domain: {"description":"Peptidase C51","evidences":[{"source":"PROSITE-ProRule","id":"PRU00048","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	440
Details	Region: {"description":"Interacts with large extracellular loop of FtsX","evidences":[{"source":"PubMed","id":"30696736","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	72
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---