4CG1

Structural and functional studies on a thermostable polyethylene terephthalate degrading hydrolase from Thermobifida fusca

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0042597	cellular_component	periplasmic space
A	0050525	molecular_function	cutinase activity
A	0052689	molecular_function	carboxylic ester hydrolase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SO4 A 1264

Chain	Residue
A	VAL24
A	ARG46
A	ARG256
A	SER257
A	HOH2074
A	HOH2274
A	HOH2334
A	HOH2335
A	HOH2339

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 1265

Chain	Residue
A	SER30
A	ARG31
A	LEU32
A	ARG46
A	ARG256
A	HOH2077
A	HOH2340

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Functional Information from PROSITE/UniProt

site_id	PS00120
Number of Residues	10
Details	LIPASE_SER Lipases, serine active site. LAVMGHSMGG

Chain	Residue	Details
A	LEU124-GLY133

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Nucleophile => ECO:0000269|PubMed:24728714, ECO:0007744|PDB:4CG2

Chain	Residue	Details
A	ILE170

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site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: Charge relay system => ECO:0000250|UniProtKB:A0A0K8P6T7

Chain	Residue	Details
A	LYS216
A	LEU248

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site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250|UniProtKB:A0A0K8P6T7, ECO:0000305|PubMed:24728714

Chain	Residue	Details
A	LEU100
A	ILE171

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site_id	SWS_FT_FI4
Number of Residues	1
Details	BINDING: BINDING => ECO:0000250|UniProtKB:A0A0K8P6T7

Chain	Residue	Details
A	SER195

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