4CE0

Crystal Structure of SAH-bound Spinosyn Rhamnosyl 4'-O- Methyltransferase SpnH from Saccharopolyspora spinosa

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008168	molecular_function	methyltransferase activity
A	0016740	molecular_function	transferase activity
A	0017000	biological_process	antibiotic biosynthetic process
A	0032259	biological_process	methylation
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE SAH A 1250

Chain	Residue
A	THR53
A	LEU139
A	GLY165
A	TRP166
A	PHE167
A	ASP185
A	SER191
A	HOH2085
A	MET54
A	GLU81
A	GLY83
A	TRP85
A	ASP111
A	SER112
A	GLY115
A	MET116

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 1251

Chain	Residue
A	ASP185
A	ASP212
A	ASP213
A	HOH2021
A	HOH2027
A	HOH2090

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