4CDC
Human DPP1 in complex with (2S)-2-amino-N-((1S)-1-cyano-2-(4- phenylphenyl)ethyl)butanamide
Functional Information from GO Data
Chain | GOid | namespace | contents |
B | 0006508 | biological_process | proteolysis |
B | 0008234 | molecular_function | cysteine-type peptidase activity |
C | 0006508 | biological_process | proteolysis |
C | 0008234 | molecular_function | cysteine-type peptidase activity |
E | 0006508 | biological_process | proteolysis |
E | 0008234 | molecular_function | cysteine-type peptidase activity |
F | 0006508 | biological_process | proteolysis |
F | 0008234 | molecular_function | cysteine-type peptidase activity |
H | 0006508 | biological_process | proteolysis |
H | 0008234 | molecular_function | cysteine-type peptidase activity |
I | 0006508 | biological_process | proteolysis |
I | 0008234 | molecular_function | cysteine-type peptidase activity |
K | 0006508 | biological_process | proteolysis |
K | 0008234 | molecular_function | cysteine-type peptidase activity |
L | 0006508 | biological_process | proteolysis |
L | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PROSITE/UniProt
site_id | PS00639 |
Number of Residues | 11 |
Details | THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. TNHAVLLVGYG |
Chain | Residue | Details |
C | THR379-GLY389 |
site_id | PS00640 |
Number of Residues | 20 |
Details | THIOL_PROTEASE_ASN Eukaryotic thiol (cysteine) proteases asparagine active site. YWIvKNSWgtgWGenGYFrI |
Chain | Residue | Details |
C | TYR398-ILE417 |
site_id | PS00139 |
Number of Residues | 12 |
Details | THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QAsCGSCYSfAS |
Chain | Residue | Details |
B | GLN228-SER239 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10089 |
Chain | Residue | Details |
C | HIS381 | |
F | HIS381 | |
I | HIS381 | |
L | HIS381 |
site_id | SWS_FT_FI2 |
Number of Residues | 4 |
Details | ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10090 |
Chain | Residue | Details |
C | ASN403 | |
K | PHE278 | |
K | TYR280 | |
K | TYR323 | |
F | ASN403 | |
I | ASN403 | |
L | ASN403 | |
E | TYR280 | |
E | TYR323 | |
H | PHE278 | |
H | TYR280 | |
H | TYR323 |
site_id | SWS_FT_FI3 |
Number of Residues | 4 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19167329 |
Chain | Residue | Details |
B | ASN252 | |
E | ASN252 | |
H | ASN252 | |
K | ASN252 |