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4CCM

60S ribosomal protein L8 histidine hydroxylase (NO66) in complex with Mn(II), N-oxalylglycine (NOG) and 60S ribosomal protein L8 (RPL8 G220C) peptide fragment (complex-1)

Functional Information from GO Data
ChainGOidnamespacecontents
C0003735molecular_functionstructural constituent of ribosome
C0005840cellular_componentribosome
C0006412biological_processtranslation
D0003735molecular_functionstructural constituent of ribosome
D0005840cellular_componentribosome
D0006412biological_processtranslation
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MN A 901
ChainResidue
AHIS340
AASP342
AHIS405
AOGA902
AHOH2075

site_idAC2
Number of Residues12
DetailsBINDING SITE FOR RESIDUE OGA A 902
ChainResidue
ALYS355
ATRP357
AHIS405
AHIS417
ATHR419
AMN901
AHOH2075
AHOH2079
ATYR328
APHE337
AHIS340
AASP342

site_idAC3
Number of Residues3
DetailsBINDING SITE FOR RESIDUE EDO A 903
ChainResidue
AARG452
AHOH2188
BGLU224

site_idAC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MN B 901
ChainResidue
BHIS340
BASP342
BHIS405
BOGA902
BHOH2068

site_idAC5
Number of Residues12
DetailsBINDING SITE FOR RESIDUE OGA B 902
ChainResidue
BTYR328
BPHE337
BHIS340
BASP342
BLYS355
BHIS405
BHIS417
BTHR419
BMN901
BHOH2068
BHOH2071
BHOH2072

site_idAC6
Number of Residues6
DetailsBINDING SITE FOR RESIDUE EDO B 903
ChainResidue
AGLY320
ASER321
AASN426
AARG501
AHOH2071
BPHE458

site_idAC7
Number of Residues6
DetailsBINDING SITE FOR RESIDUE EDO B 904
ChainResidue
APHE458
BGLY320
BSER321
BASN426
BARG501
BHOH2065

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: (3S)-3-hydroxyhistidine => ECO:0000269|PubMed:23103944
ChainResidueDetails
CHIS216
DHIS216
AHIS405
BHIS340
BASP342
BHIS405

site_idSWS_FT_FI2
Number of Residues4
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733
ChainResidueDetails
CLYS234
DLYS234

226707

PDB entries from 2024-10-30

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