4CAS

Serial femtosecond crystallography structure of a photosynthetic reaction center

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005506	molecular_function	iron ion binding
A	0009055	molecular_function	electron transfer activity
A	0019684	biological_process	photosynthesis, light reaction
A	0020037	molecular_function	heme binding
A	0030077	cellular_component	plasma membrane light-harvesting complex
B	0009772	biological_process	photosynthetic electron transport in photosystem II
B	0015979	biological_process	photosynthesis
B	0016168	molecular_function	chlorophyll binding
B	0019684	biological_process	photosynthesis, light reaction
B	0030077	cellular_component	plasma membrane light-harvesting complex
B	0042314	molecular_function	bacteriochlorophyll binding
B	0042717	cellular_component	plasma membrane-derived chromatophore membrane
B	0046872	molecular_function	metal ion binding
C	0009772	biological_process	photosynthetic electron transport in photosystem II
C	0015979	biological_process	photosynthesis
C	0016168	molecular_function	chlorophyll binding
C	0019684	biological_process	photosynthesis, light reaction
C	0030077	cellular_component	plasma membrane light-harvesting complex
C	0042314	molecular_function	bacteriochlorophyll binding
C	0042717	cellular_component	plasma membrane-derived chromatophore membrane
C	0046872	molecular_function	metal ion binding
D	0015979	biological_process	photosynthesis
D	0016168	molecular_function	chlorophyll binding
D	0019684	biological_process	photosynthesis, light reaction
D	0030077	cellular_component	plasma membrane light-harvesting complex
D	0042314	molecular_function	bacteriochlorophyll binding
D	0042717	cellular_component	plasma membrane-derived chromatophore membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	binding site for residue HEC A 401

Chain	Residue
A	TYR56
A	THR78
A	SER82
A	CYS87
A	CYS90
A	HIS91
A	TYR104
A	ALA107
A	ARG108
A	LYS57
A	ASN58
A	VAL59
A	LYS60
A	VAL61
A	LEU62
A	PHE70
A	MET74

---

site_id	AC2
Number of Residues	17
Details	binding site for residue HEC A 402

Chain	Residue
A	VAL81
A	TYR89
A	TYR102
A	VAL106
A	MET110
A	MET113
A	THR114
A	CYS132
A	CYS135
A	HIS136
A	PRO140
A	LEU141
A	PRO142
A	LEU289
A	ARG293
A	PRO301
A	HEC404

---

site_id	AC3
Number of Residues	18
Details	binding site for residue HEC A 403

Chain	Residue
A	VAL201
A	ARG202
A	VAL203
A	VAL204
A	MET233
A	SER237
A	ASN243
A	CYS244
A	CYS247
A	HIS248
A	PHE253
A	GLU254
A	ARG264
A	ALA267
A	TRP268
A	ARG272
B	TYR162
C	ILE189

---

site_id	AC4
Number of Residues	16
Details	binding site for residue HEC A 404

Chain	Residue
A	HIS124
A	THR128
A	GLY129
A	LEU240
A	GLN263
A	ALA267
A	ILE271
A	MET273
A	ASP304
A	CYS305
A	CYS308
A	HIS309
A	THR313
A	LYS314
A	PRO315
A	HEC402

---

site_id	AC5
Number of Residues	3
Details	binding site for residue DGA A 405

Chain	Residue
A	CYS1
B	TRP262
B	TRP265

---

site_id	AC6
Number of Residues	11
Details	binding site for residue BCL B 301

Chain	Residue
B	MET174
B	VAL177
B	PHE181
B	MET185
B	BCL302
C	MET120
C	VAL155
C	HIS180
C	BCL402
C	BPB403
C	NS5405

---

site_id	AC7
Number of Residues	20
Details	binding site for residue BCL B 302

Chain	Residue
B	BPB304
C	TYR195
C	BCL402
B	PHE97
B	PRO124
B	MET127
B	PHE128
B	LEU131
B	VAL157
B	ASN158
B	PHE160
B	TRP167
B	HIS168
B	HIS173
B	SER176
B	PHE241
B	GLY244
B	THR248
B	BCL301
B	BCL303

---

site_id	AC8
Number of Residues	16
Details	binding site for residue BCL B 303

Chain	Residue
B	ILE49
B	PHE128
B	PHE146
B	ILE150
B	HIS153
B	LEU154
B	VAL157
B	BCL302
B	BPB304
C	TYR195
C	GLY201
C	ILE204
C	GLY205
C	TYR208
C	BCL402
C	OTP406

---

site_id	AC9
Number of Residues	18
Details	binding site for residue BPB B 304

Chain	Residue
B	ILE42
B	ILE49
B	ALA93
B	TRP100
B	GLU104
B	VAL117
B	PHE121
B	PRO124
B	TYR148
B	GLY149
B	ILE150
B	HIS153
B	ALA237
B	BCL302
B	BCL303
C	TYR208
C	LEU212
C	MQ7404

---

site_id	AD1
Number of Residues	3
Details	binding site for residue MPG B 305

Chain	Residue
B	LEU119
B	SER238
C	ALA1

---

site_id	AD2
Number of Residues	5
Details	binding site for residue MPG B 306

Chain	Residue
B	PHE179
B	LEU189
B	HIS190
B	PHE216
B	SER223

---

site_id	AD3
Number of Residues	5
Details	binding site for residue FE2 C 401

Chain	Residue
B	HIS190
B	HIS230
C	HIS217
C	GLU232
C	HIS264

---

site_id	AD4
Number of Residues	19
Details	binding site for residue BCL C 402

Chain	Residue
B	HIS168
B	BCL301
B	BCL302
B	BCL303
C	ILE69
C	MET120
C	PHE148
C	PHE154
C	THR185
C	PHE194
C	TYR195
C	HIS200
C	SER203
C	ILE204
C	TYR208
C	MET275
C	ALA278
C	ILE282
C	BPB403

---

site_id	AD5
Number of Residues	14
Details	binding site for residue BPB C 403

Chain	Residue
B	PHE181
B	MET185
B	LEU189
B	BCL301
C	SER63
C	SER123
C	TRP127
C	ILE144
C	ASN147
C	PHE148
C	SER271
C	MET275
C	BCL402
C	NS5405

---

site_id	AD6
Number of Residues	12
Details	binding site for residue MQ7 C 404

Chain	Residue
B	TYR29
B	ILE39
B	ARG103
B	BPB304
C	HIS217
C	THR220
C	ALA246
C	ALA247
C	TRP250
C	ASN257
C	ALA258
C	TRP266

---

site_id	AD7
Number of Residues	8
Details	binding site for residue NS5 C 405

Chain	Residue
B	BCL301
C	GLY117
C	THR121
C	VAL155
C	GLY159
C	CYS160
C	GLY176
C	BPB403

---

site_id	AD8
Number of Residues	7
Details	binding site for residue OTP C 406

Chain	Residue
B	PHE62
B	LEU151
B	BCL303
C	PRO198
C	PHE206
C	CYS296
D	TRP25

---

site_id	AD9
Number of Residues	6
Details	binding site for residue PO4 C 408

Chain	Residue
C	TRP23
C	TYR50
C	GLY52
C	ALA53
C	SER54
C	SER133

---

site_id	AE1
Number of Residues	1
Details	binding site for residue PO4 C 409

Chain	Residue
C	ARG265

---

Functional Information from PROSITE/UniProt

site_id	PS00244
Number of Residues	27
Details	REACTION_CENTER Photosynthetic reaction center proteins signature. NfyycPwHgfSigfaygcgllfAaHGA

Chain	Residue	Details
C	ASN193-ALA219
B	ASN166-GLY192

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"22054235","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3T6E","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"description":"covalent","evidences":[{"source":"PubMed","id":"22054235","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3T6E","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Site: {"description":"Not N-palmitoylated","evidences":[{"source":"PubMed","id":"22054235","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"journal article","publicationDate":"1987","firstPage":"2909","lastPage":"2914","volume":"26","journal":"Biochemistry","title":"The cytochrome subunit of the photosynthetic reaction center from Rhodopseudomonas viridis is a lipoprotein.","authors":["Weyer K.A.","Schaefer W.","Lottspeich F.","Michel H."]}},{"source":"PDB","id":"3T6E","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Lipidation: {"description":"S-diacylglycerol cysteine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00303","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"22054235","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"journal article","publicationDate":"1987","firstPage":"2909","lastPage":"2914","volume":"26","journal":"Biochemistry","title":"The cytochrome subunit of the photosynthetic reaction center from Rhodopseudomonas viridis is a lipoprotein.","authors":["Weyer K.A.","Schaefer W.","Lottspeich F.","Michel H."]}},{"source":"PDB","id":"3T6E","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	147
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"2676514","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	260
Details	Transmembrane: {"description":"Helical"}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	185
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"2676514","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	4
Details	Binding site: {"description":"axial binding residue"}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	7
Details	Binding site: {}

Chain

Residue

Details

---