4C81
IspF (Plasmodium falciparum) CDP complex
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 1240 |
| Chain | Residue |
| A | ASP71 |
| A | HIS73 |
| A | HIS123 |
| A | CDP1242 |
| A | HOH2009 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 1241 |
| Chain | Residue |
| A | CL1246 |
| A | TYR70 |
| A | HIS215 |
| A | GLU228 |
| A | CL1244 |
| site_id | AC3 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE CDP A 1242 |
| Chain | Residue |
| A | ASP137 |
| A | GLY139 |
| A | THR140 |
| A | ALA181 |
| A | PRO184 |
| A | LYS185 |
| A | ILE186 |
| A | SER187 |
| A | GLY212 |
| A | LYS213 |
| A | THR214 |
| A | GLU216 |
| A | ZN1240 |
| A | HOH2008 |
| A | HOH2009 |
| A | HOH2010 |
| A | HOH2040 |
| A | HOH2041 |
| A | HOH2081 |
| A | HOH2082 |
| A | HOH2083 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 1244 |
| Chain | Residue |
| A | HIS215 |
| A | ILE221 |
| A | ZN1241 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 1245 |
| Chain | Residue |
| A | HIS73 |
| A | LYS74 |
| A | LEU113 |
| A | GLU216 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 1246 |
| Chain | Residue |
| A | HIS215 |
| A | GLU228 |
| A | GLU228 |
| A | ZN1241 |
| site_id | AC7 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1247 |
| Chain | Residue |
| A | GLY219 |
| A | GLY219 |
| A | GLY219 |
| A | VAL220 |
| A | VAL220 |
| A | VAL220 |
| A | HOH2077 |
| A | HOH2077 |
| A | HOH2077 |
| A | HOH2085 |
| A | HOH2085 |
| A | HOH2085 |
Functional Information from PROSITE/UniProt
| site_id | PS01350 |
| Number of Residues | 16 |
| Details | ISPF 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. SDGDIIyHSivDSilG |
| Chain | Residue | Details |
| A | SER116-GLY131 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P62617","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24410837","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4C81","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4C82","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24410837","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4C81","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Transition state stabilizer","evidences":[{"source":"UniProtKB","id":"P62617","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
