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4C7L

Crystal structure of Mouse Hepatitis virus strain S Hemagglutinin- esterase

Functional Information from GO Data
ChainGOidnamespacecontents
A0001681molecular_functionsialate O-acetylesterase activity
A0016020cellular_componentmembrane
A0016787molecular_functionhydrolase activity
A0016788molecular_functionhydrolase activity, acting on ester bonds
A0019031cellular_componentviral envelope
A0019064biological_processfusion of virus membrane with host plasma membrane
A0020002cellular_componenthost cell plasma membrane
A0033644cellular_componenthost cell membrane
A0044423cellular_componentvirion component
A0044650biological_processadhesion of symbiont to host cell
A0046789molecular_functionhost cell surface receptor binding
A0055036cellular_componentvirion membrane
A0106330molecular_functionsialate 9-O-acetylesterase activity
A0106331molecular_functionsialate 4-O-acetylesterase activity
B0001681molecular_functionsialate O-acetylesterase activity
B0016020cellular_componentmembrane
B0016787molecular_functionhydrolase activity
B0016788molecular_functionhydrolase activity, acting on ester bonds
B0019031cellular_componentviral envelope
B0019064biological_processfusion of virus membrane with host plasma membrane
B0020002cellular_componenthost cell plasma membrane
B0033644cellular_componenthost cell membrane
B0044423cellular_componentvirion component
B0044650biological_processadhesion of symbiont to host cell
B0046789molecular_functionhost cell surface receptor binding
B0055036cellular_componentvirion membrane
B0106330molecular_functionsialate 9-O-acetylesterase activity
B0106331molecular_functionsialate 4-O-acetylesterase activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: Nucleophile => ECO:0000255|HAMAP-Rule:MF_04207, ECO:0000269|PubMed:22291594
ChainResidueDetails
AALA45
BALA45

site_idSWS_FT_FI2
Number of Residues4
DetailsACT_SITE: Charge relay system => ECO:0000255|HAMAP-Rule:MF_04207, ECO:0000269|PubMed:22291594
ChainResidueDetails
AASP342
AHIS345
BASP342
BHIS345

site_idSWS_FT_FI3
Number of Residues16
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04207, ECO:0000269|PubMed:22291594
ChainResidueDetails
AASN94
BASN152
BASN196
BASN246
BASN316
BASN331
BASN360
BASN374
AASN152
AASN196
AASN246
AASN316
AASN331
AASN360
AASN374
BASN94

site_idSWS_FT_FI4
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04207
ChainResidueDetails
AASN309
BASN309

218853

PDB entries from 2024-04-24

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