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4C73

Crystal structure of M. tuberculosis C171Q KasA in complex with TLM6

Functional Information from GO Data
ChainGOidnamespacecontents
A0016746molecular_functionacyltransferase activity
B0016746molecular_functionacyltransferase activity
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE EDO A 1417
ChainResidue
AALA18
AVAL19
AGLU30
AHOH2015

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO A 1418
ChainResidue
AASP69
ATYR82
APRO201
AM7U1428
AHOH2107

site_idAC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO A 1419
ChainResidue
AARG121
AGLU124
ASER125
ALEU128
ASER138

site_idAC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE EDO A 1420
ChainResidue
AASN130
AHOH2409
AHOH2410
BTRP54

site_idAC5
Number of Residues7
DetailsBINDING SITE FOR RESIDUE EDO A 1421
ChainResidue
ASER211
AARG214
AALA215
AMET216
ATHR218
AEDO1431
AHOH2411

site_idAC6
Number of Residues8
DetailsBINDING SITE FOR RESIDUE EDO A 1422
ChainResidue
APHE275
APRO280
AALA282
AILE317
ATYR391
AEDO1424
AHOH2349
AHOH2412

site_idAC7
Number of Residues6
DetailsBINDING SITE FOR RESIDUE EDO A 1423
ChainResidue
AASP283
AVAL285
AARG286
AHOH2322
AHOH2413
AHOH2414

site_idAC8
Number of Residues6
DetailsBINDING SITE FOR RESIDUE EDO A 1424
ChainResidue
APHE275
AALA282
AASP283
AEDO1422
AHOH2415
AHOH2416

site_idAC9
Number of Residues6
DetailsBINDING SITE FOR RESIDUE K A 1425
ChainResidue
AASN309
AALA310
AHIS311
AGLU354
AASN399
AASN400

site_idBC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO A 1426
ChainResidue
AASP332
AGLN333
AASP381
AHOH2365
AHOH2417

site_idBC2
Number of Residues14
DetailsBINDING SITE FOR RESIDUE TLH A 1427
ChainResidue
AGLN171
APHE237
AVAL278
AALA279
APRO280
AHIS311
ATHR313
ATHR315
AHIS345
APHE402
AGLY403
APHE404
AGLY406
AHOH2346

site_idBC3
Number of Residues20
DetailsBINDING SITE FOR RESIDUE M7U A 1428
ChainResidue
AGLY115
AGLU120
AALA170
AGLU199
AGLY200
APRO201
AILE202
AGLU203
ALEU205
AALA209
APHE239
AGLY240
AGLU241
ASER346
AILE347
AEDO1418
AEDO1430
AHOH2194
BVAL142
BILE145

site_idBC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO A 1429
ChainResidue
ATHR292
AGLU296
ALEU300
APRO302
AHOH2418

site_idBC5
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO A 1430
ChainResidue
AHOH2144
AARG85
AGLU120
AM7U1428
AHOH2130

site_idBC6
Number of Residues4
DetailsBINDING SITE FOR RESIDUE EDO B 1417
ChainResidue
ATRP54
AHOH2252
BASN130
BHOH2312

site_idBC7
Number of Residues6
DetailsBINDING SITE FOR RESIDUE K B 1418
ChainResidue
BASN309
BALA310
BHIS311
BGLU354
BASN399
BASN400

site_idBC8
Number of Residues4
DetailsBINDING SITE FOR RESIDUE EDO B 1419
ChainResidue
BSER211
BARG214
BALA215
BMET216

site_idBC9
Number of Residues6
DetailsBINDING SITE FOR RESIDUE EDO B 1420
ChainResidue
BVAL384
BVAL385
BALA386
BARG390
BHOH2297
BHOH2298

site_idCC1
Number of Residues16
DetailsBINDING SITE FOR RESIDUE TLH B 1421
ChainResidue
BGLN171
BALA215
BPHE237
BHIS276
BVAL278
BALA279
BPRO280
BHIS311
BTHR313
BTHR315
BHIS345
BPHE402
BGLY403
BPHE404
BGLY406
BHOH2252

site_idCC2
Number of Residues14
DetailsBINDING SITE FOR RESIDUE M7U B 1422
ChainResidue
AILE145
BGLY115
BGLU120
BALA170
BGLY200
BPRO201
BGLU203
BALA209
BPHE239
BGLY240
BGLU241
BHIS345
BILE347
BEDO1423

site_idCC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO B 1423
ChainResidue
BASP69
BM7U1422
BHOH2080
BHOH2082
BHOH2314

site_idCC4
Number of Residues2
DetailsBINDING SITE FOR RESIDUE EDO B 1424
ChainResidue
BASN130
BGLY132

site_idCC5
Number of Residues4
DetailsBINDING SITE FOR RESIDUE EDO B 1425
ChainResidue
AARG74
AARG78
BGLN333
BHOH2273

site_idCC6
Number of Residues7
DetailsBINDING SITE FOR RESIDUE EDO A 1431
ChainResidue
AALA57
ASER211
AARG214
AEDO1421
AHOH2101
AHOH2419
BARG135

site_idCC7
Number of Residues3
DetailsBINDING SITE FOR RESIDUE EDO A 1432
ChainResidue
AARG79
AGLN84
AGLN143

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PDB entries from 2024-10-30

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