Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4C5O

Flavin monooxygenase from Stenotrophomonas maltophilia. Q193R H194T mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004497	molecular_function	monooxygenase activity
A	0005829	cellular_component	cytosol
A	0009851	biological_process	auxin biosynthetic process
A	0050660	molecular_function	flavin adenine dinucleotide binding
B	0000166	molecular_function	nucleotide binding
B	0004497	molecular_function	monooxygenase activity
B	0005829	cellular_component	cytosol
B	0009851	biological_process	auxin biosynthetic process
B	0050660	molecular_function	flavin adenine dinucleotide binding
C	0000166	molecular_function	nucleotide binding
C	0004497	molecular_function	monooxygenase activity
C	0005829	cellular_component	cytosol
C	0009851	biological_process	auxin biosynthetic process
C	0050660	molecular_function	flavin adenine dinucleotide binding
D	0000166	molecular_function	nucleotide binding
D	0004497	molecular_function	monooxygenase activity
D	0005829	cellular_component	cytosol
D	0009851	biological_process	auxin biosynthetic process
D	0050660	molecular_function	flavin adenine dinucleotide binding
E	0000166	molecular_function	nucleotide binding
E	0004497	molecular_function	monooxygenase activity
E	0005829	cellular_component	cytosol
E	0009851	biological_process	auxin biosynthetic process
E	0050660	molecular_function	flavin adenine dinucleotide binding
F	0000166	molecular_function	nucleotide binding
F	0004497	molecular_function	monooxygenase activity
F	0005829	cellular_component	cytosol
F	0009851	biological_process	auxin biosynthetic process
F	0050660	molecular_function	flavin adenine dinucleotide binding
G	0000166	molecular_function	nucleotide binding
G	0004497	molecular_function	monooxygenase activity
G	0005829	cellular_component	cytosol
G	0009851	biological_process	auxin biosynthetic process
G	0050660	molecular_function	flavin adenine dinucleotide binding
H	0000166	molecular_function	nucleotide binding
H	0004497	molecular_function	monooxygenase activity
H	0005829	cellular_component	cytosol
H	0009851	biological_process	auxin biosynthetic process
H	0050660	molecular_function	flavin adenine dinucleotide binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	23
Details	BINDING SITE FOR RESIDUE FAD A 1353

Chain	Residue
A	GLY10
A	TRP42
A	TRP46
A	LEU51
A	PHE52
A	ILE97
A	VAL99
A	ALA127
A	THR128
A	GLY129
A	SER174
A	GLY12
A	ALA331
A	THR332
A	LEU333
A	HOH2004
A	GLN13
A	SER14
A	ASP33
A	ALA34
A	GLU35
A	GLY40
A	ALA41

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 1354

Chain	Residue
A	ARG98
A	ARG114

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 1355

Chain	Residue
A	GLN149
A	LEU150
A	HIS151
A	HIS154
B	GLN100

site_id	AC4
Number of Residues	26
Details	BINDING SITE FOR RESIDUE FAD B 1353

Chain	Residue
B	GLY10
B	GLY12
B	GLN13
B	SER14
B	LEU32
B	ASP33
B	ALA34
B	GLU35
B	GLY40
B	ALA41
B	TRP42
B	TRP46
B	LEU49
B	LEU51
B	PHE52
B	ILE97
B	VAL99
B	ALA127
B	THR128
B	GLY129
B	SER174
B	ALA331
B	THR332
B	LEU333
B	HOH2001
B	HOH2003

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 1354

Chain	Residue
B	ARG98
B	ARG114

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 1355

Chain	Residue
B	HIS44
B	TRP131
B	ALA153
B	HIS154

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 1356

Chain	Residue
A	TRP57
A	ARG206
B	TRP57
B	ARG206

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 1357

Chain	Residue
B	GLY323
B	ASP324
B	TRP325

site_id	AC9
Number of Residues	26
Details	BINDING SITE FOR RESIDUE FAD C 1353

Chain	Residue
C	GLY10
C	GLY11
C	GLY12
C	GLN13
C	SER14
C	ASP33
C	ALA34
C	GLU35
C	GLY40
C	ALA41
C	TRP42
C	TRP46
C	LEU51
C	PHE52
C	ILE97
C	ARG98
C	VAL99
C	ALA127
C	THR128
C	GLY129
C	SER174
C	ALA331
C	THR332
C	LEU333
C	HOH2001
C	HOH2009

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 C 1354

Chain	Residue
C	ARG98
C	ARG114

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 1355

Chain	Residue
C	ALA153
C	HIS154
C	HIS44
C	TRP131

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 C 1356

Chain	Residue
C	GLY147
C	ILE148
C	GLN149
D	ARG101
D	VAL112

site_id	BC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 C 1357

Chain	Residue
C	GLY172
C	ASN173
C	SER174

site_id	BC5
Number of Residues	25
Details	BINDING SITE FOR RESIDUE FAD D 1353

Chain	Residue
D	GLY10
D	GLY12
D	GLN13
D	SER14
D	LEU32
D	ASP33
D	ALA34
D	GLU35
D	GLY40
D	ALA41
D	TRP42
D	TRP46
D	LEU49
D	LEU51
D	PHE52
D	ILE97
D	VAL99
D	THR128
D	GLY129
D	SER174
D	ALA331
D	THR332
D	LEU333
D	HOH2002
D	HOH2011

site_id	BC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 D 1354

Chain	Residue
D	ARG98
D	ARG114

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 D 1355

Chain	Residue
D	HIS44
D	TRP131
D	ALA153
D	HIS154

site_id	BC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 D 1356

Chain	Residue
C	GLN100
D	LEU150
D	HIS151
D	HIS154

site_id	BC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 1357

Chain	Residue
D	ARG206
G	GLY56
G	TRP57

site_id	CC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 1358

Chain	Residue
D	GLY323
D	ASP324
D	TRP325

site_id	CC2
Number of Residues	24
Details	BINDING SITE FOR RESIDUE FAD E 1353

Chain	Residue
E	GLY10
E	GLY12
E	GLN13
E	SER14
E	ASP33
E	ALA34
E	GLU35
E	GLY40
E	ALA41
E	TRP42
E	TRP46
E	LEU51
E	PHE52
E	ILE97
E	ARG98
E	VAL99
E	ALA127
E	THR128
E	GLY129
E	SER174
E	ALA331
E	THR332
E	LEU333
E	HOH2012

site_id	CC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 E 1354

Chain	Residue
E	ARG98
E	ARG114

site_id	CC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 E 1355

Chain	Residue
E	HIS44
E	TRP131
E	ALA153
E	HIS154

site_id	CC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 E 1356

Chain	Residue
E	GLY171
E	THR192
E	ARG193
E	THR194

site_id	CC6
Number of Residues	24
Details	BINDING SITE FOR RESIDUE FAD F 1353

Chain	Residue
F	GLY10
F	GLY12
F	GLN13
F	SER14
F	ASP33
F	ALA34
F	GLU35
F	GLY40
F	ALA41
F	TRP42
F	TRP46
F	LEU51
F	PHE52
F	ILE97
F	ARG98
F	VAL99
F	THR128
F	GLY129
F	SER174
F	ALA331
F	THR332
F	LEU333
F	HOH2001
F	HOH2003

site_id	CC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 F 1354

Chain	Residue
F	ARG98
F	ARG114

site_id	CC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 F 1355

Chain	Residue
F	GLY171
F	THR192
F	ARG193
F	THR194

site_id	CC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 F 1356

Chain	Residue
F	GLY172
F	ASN173

site_id	DC1
Number of Residues	24
Details	BINDING SITE FOR RESIDUE FAD G 1353

Chain	Residue
G	GLY10
G	GLY12
G	GLN13
G	SER14
G	ASP33
G	ALA34
G	GLU35
G	GLY40
G	ALA41
G	TRP42
G	TRP46
G	LEU51
G	PHE52
G	ILE97
G	VAL99
G	ALA127
G	THR128
G	GLY129
G	SER174
G	ALA331
G	THR332
G	LEU333
G	HOH2001
G	HOH2009

site_id	DC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 G 1354

Chain	Residue
G	ARG98
G	ARG114

site_id	DC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 G 1355

Chain	Residue
G	ARG310
G	TYR350

site_id	DC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 G 1356

Chain	Residue
G	GLY171
G	THR192
G	ARG193

site_id	DC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 G 1357

Chain	Residue
G	GLY172
G	ASN173

site_id	DC6
Number of Residues	24
Details	BINDING SITE FOR RESIDUE FAD H 1353

Chain	Residue
H	GLY10
H	GLY12
H	GLN13
H	SER14
H	ASP33
H	ALA34
H	GLU35
H	GLY40
H	ALA41
H	TRP42
H	TRP46
H	LEU51
H	PHE52
H	ILE97
H	VAL99
H	ALA127
H	THR128
H	GLY129
H	SER174
H	ALA331
H	THR332
H	LEU333
H	HOH2001
H	HOH2020

site_id	DC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 H 1354

Chain	Residue
H	ARG98
H	ARG114

site_id	DC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 H 1355

Chain	Residue
H	HIS44
H	TRP131
H	ALA153
H	HIS154

site_id	DC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 H 1356

Chain	Residue
H	GLN301
H	ASP324
H	TRP325

site_id	EC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 H 1357

Chain	Residue
H	GLY171
H	THR192
H	ARG193
H	THR194

site_id	EC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 C 1358

Chain	Residue
C	GLY170
C	GLY171
C	THR192
C	ARG193
C	THR194

site_id	EC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 D 1359

Chain	Residue
D	GLY170
D	GLY171
D	THR192
D	ARG193
D	THR194

site_id	EC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 1356

Chain	Residue
A	GLY170
A	GLY171
A	THR192
A	ARG193

site_id	EC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 F 1357

Chain	Residue
F	PRO96
F	ILE97
F	ARG98
F	ALA113
F	ARG114
F	ASP115
F	ARG117

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)