4C5N
Structure of the pyridoxal kinase from Staphylococcus aureus in complex with AMP-PCP and pyridoxal
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008972 | molecular_function | phosphomethylpyrimidine kinase activity |
| A | 0009228 | biological_process | thiamine biosynthetic process |
| B | 0008972 | molecular_function | phosphomethylpyrimidine kinase activity |
| B | 0009228 | biological_process | thiamine biosynthetic process |
| C | 0008972 | molecular_function | phosphomethylpyrimidine kinase activity |
| C | 0009228 | biological_process | thiamine biosynthetic process |
| D | 0008972 | molecular_function | phosphomethylpyrimidine kinase activity |
| D | 0009228 | biological_process | thiamine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PXL A 300 |
| Chain | Residue |
| A | GLY11 |
| A | SER12 |
| A | ASP13 |
| A | GLY19 |
| A | CYS214 |
| A | ACP500 |
| A | HOH2007 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE ACP A 500 |
| Chain | Residue |
| A | ASP188 |
| A | ASP202 |
| A | MET203 |
| A | PHE204 |
| A | GLN205 |
| A | ASN209 |
| A | HIS210 |
| A | GLY211 |
| A | ALA212 |
| A | GLY213 |
| A | CYS214 |
| A | LYS238 |
| A | ILE245 |
| A | PXL300 |
| A | HOH2051 |
| A | HOH2056 |
| A | LYS176 |
| A | SER186 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PXL B 300 |
| Chain | Residue |
| B | GLY11 |
| B | SER12 |
| B | ASP13 |
| B | GLY19 |
| B | VAL42 |
| B | MET80 |
| B | VAL107 |
| B | HIS210 |
| B | CYS214 |
| B | ACP500 |
| B | HOH2005 |
| site_id | AC4 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE ACP B 500 |
| Chain | Residue |
| B | LYS176 |
| B | GLY178 |
| B | SER186 |
| B | ASP188 |
| B | ASP202 |
| B | MET203 |
| B | PHE204 |
| B | GLN205 |
| B | GLN206 |
| B | ASN209 |
| B | HIS210 |
| B | GLY211 |
| B | ALA212 |
| B | GLY213 |
| B | CYS214 |
| B | LYS238 |
| B | ILE245 |
| B | PXL300 |
| B | HOH2053 |
| B | HOH2054 |
| B | HOH2062 |
| B | HOH2085 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PXL C 300 |
| Chain | Residue |
| C | GLY11 |
| C | GLY19 |
| C | CYS214 |
| C | ACP500 |
| C | HOH2009 |
| site_id | AC6 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE ACP C 500 |
| Chain | Residue |
| C | LYS176 |
| C | GLY178 |
| C | LYS179 |
| C | SER186 |
| C | ASP188 |
| C | ASP202 |
| C | MET203 |
| C | PHE204 |
| C | GLN205 |
| C | ASN209 |
| C | HIS210 |
| C | GLY211 |
| C | ALA212 |
| C | GLY213 |
| C | CYS214 |
| C | LYS238 |
| C | ILE245 |
| C | PXL300 |
| C | HOH2047 |
| C | HOH2048 |
| C | HOH2058 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE UEG D 300 |
| Chain | Residue |
| D | GLY11 |
| D | GLY19 |
| D | VAL42 |
| D | VAL109 |
| D | CYS110 |
| D | HIS210 |
| D | CYS214 |
| D | HOH2003 |
| D | HOH2016 |
| site_id | AC8 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ACP D 500 |
| Chain | Residue |
| D | PHE204 |
| D | GLN205 |
| D | ASN209 |
| D | GLY211 |
| D | ALA212 |
| D | GLY213 |
| D | CYS214 |
| D | LYS238 |
| D | ILE245 |
| D | HOH2035 |
| D | HOH2036 |
| D | ASN139 |
| D | LYS176 |
| D | GLY178 |
| D | SER186 |
| D | ASP188 |
| D | ASP202 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1277 |
| Chain | Residue |
| C | GLN205 |
| C | GLN206 |
| C | SER207 |
| D | THR274 |
| D | GLU275 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1277 |
| Chain | Residue |
| D | GLN206 |
| D | SER207 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1278 |
| Chain | Residue |
| D | GLY72 |
| D | ASN98 |
| D | HOH2019 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1279 |
| Chain | Residue |
| D | LEU30 |
| D | TYR223 |
| D | TYR263 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1277 |
| Chain | Residue |
| B | GLY72 |
| B | ASN98 |
| B | HOH2038 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1278 |
| Chain | Residue |
| A | LYS185 |
| B | HIS172 |
| B | HOH2074 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1278 |
| Chain | Residue |
| C | GLY72 |
| C | ASN98 |
| C | HOH2008 |
