Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4C56

X-ray structure of the complex between staphylococcal enterotoxin B, T cell receptor and major histocompatibility complex class II

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0035821	biological_process	modulation of process of another organism
C	0046872	molecular_function	metal ion binding
C	0090729	molecular_function	toxin activity
D	0006955	biological_process	immune response
D	0016020	cellular_component	membrane
D	0019882	biological_process	antigen processing and presentation
D	0042613	cellular_component	MHC class II protein complex
E	0006955	biological_process	immune response
E	0016020	cellular_component	membrane
E	0019882	biological_process	antigen processing and presentation
E	0042613	cellular_component	MHC class II protein complex
I	0005515	molecular_function	protein binding
I	0005576	cellular_component	extracellular region
I	0035821	biological_process	modulation of process of another organism
I	0046872	molecular_function	metal ion binding
I	0090729	molecular_function	toxin activity
J	0006955	biological_process	immune response
J	0016020	cellular_component	membrane
J	0019882	biological_process	antigen processing and presentation
J	0042613	cellular_component	MHC class II protein complex
K	0006955	biological_process	immune response
K	0016020	cellular_component	membrane
K	0019882	biological_process	antigen processing and presentation
K	0042613	cellular_component	MHC class II protein complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL E 1191

Chain	Residue
E	ARG166
E	GLU169

Functional Information from PROSITE/UniProt

site_id	PS00277
Number of Residues	10
Details	STAPH_STREP_TOXIN_1 Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin signature 1. YGGVTEHngN

Chain	Residue	Details
C	TYR115-ASN124

site_id	PS00278
Number of Residues	24
Details	STAPH_STREP_TOXIN_2 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2. KkkVtaqeLDyltRhyLvknkkLY

Chain	Residue	Details
C	LYS152-TYR175

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCQVEH

Chain	Residue	Details
E	TYR171-HIS177
D	TYR161-HIS167

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00498","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00498","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	218
Details	Domain: {"description":"Ig-like C1-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00114","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	272
Details	Domain: {"description":"Ig-like C1-type"}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	186
Details	Region: {"description":"Alpha-2"}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	2
Details	Site: {"description":"Self- and pathogen-derived peptide antigen","evidences":[{"source":"PubMed","id":"17583734","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21115828","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23260142","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8145819","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4GBX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	4
Details	Site: {"description":"Self-peptide antigen","evidences":[{"source":"PubMed","id":"31619516","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	2
Details	Site: {"description":"Self- and pathogen-derived peptide antigen","evidences":[{"source":"PubMed","id":"21115828","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8145819","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	2
Details	Site: {"description":"Self- and pathogen-derived peptide antigen","evidences":[{"source":"PubMed","id":"17583734","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21115828","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31619516","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8145819","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	2
Details	Site: {"description":"Pathogen-derived peptide antigen","evidences":[{"source":"PubMed","id":"23260142","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4GBX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	2
Details	Site: {"description":"Self- and pathogen-derived peptide antigen","evidences":[{"source":"PubMed","id":"17583734","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21115828","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23260142","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31619516","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8145819","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4GBX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	2
Details	Site: {"description":"Pathogen-derived peptide antigen","evidences":[{"source":"PubMed","id":"17583734","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21115828","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23260142","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8145819","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4FQX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4GBX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	2
Details	Site: {"description":"Self- and pathogen-derived peptide antigen","evidences":[{"source":"PubMed","id":"17583734","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23260142","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31619516","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8145819","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4FQX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4GBX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI15
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7477400","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI16
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31619516","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8145819","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI17
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"8145819","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI18
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19303388","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24190431","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)