4C2D

Crystal structure of the protease CtpB in an active state

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004175	molecular_function	endopeptidase activity
A	0004252	molecular_function	serine-type endopeptidase activity
A	0005515	molecular_function	protein binding
A	0006508	biological_process	proteolysis
A	0006518	biological_process	peptide metabolic process
A	0007165	biological_process	signal transduction
A	0008233	molecular_function	peptidase activity
A	0008236	molecular_function	serine-type peptidase activity
A	0016787	molecular_function	hydrolase activity
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0030435	biological_process	sporulation resulting in formation of a cellular spore
A	0042277	molecular_function	peptide binding
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
B	0004175	molecular_function	endopeptidase activity
B	0004252	molecular_function	serine-type endopeptidase activity
B	0005515	molecular_function	protein binding
B	0006508	biological_process	proteolysis
B	0006518	biological_process	peptide metabolic process
B	0007165	biological_process	signal transduction
B	0008233	molecular_function	peptidase activity
B	0008236	molecular_function	serine-type peptidase activity
B	0016787	molecular_function	hydrolase activity
B	0030288	cellular_component	outer membrane-bounded periplasmic space
B	0030435	biological_process	sporulation resulting in formation of a cellular spore
B	0042277	molecular_function	peptide binding
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
C	0004175	molecular_function	endopeptidase activity
C	0004252	molecular_function	serine-type endopeptidase activity
C	0005515	molecular_function	protein binding
C	0006508	biological_process	proteolysis
C	0006518	biological_process	peptide metabolic process
C	0007165	biological_process	signal transduction
C	0008233	molecular_function	peptidase activity
C	0008236	molecular_function	serine-type peptidase activity
C	0016787	molecular_function	hydrolase activity
C	0030288	cellular_component	outer membrane-bounded periplasmic space
C	0030435	biological_process	sporulation resulting in formation of a cellular spore
C	0042277	molecular_function	peptide binding
C	0042802	molecular_function	identical protein binding
C	0042803	molecular_function	protein homodimerization activity
D	0004175	molecular_function	endopeptidase activity
D	0004252	molecular_function	serine-type endopeptidase activity
D	0005515	molecular_function	protein binding
D	0006508	biological_process	proteolysis
D	0006518	biological_process	peptide metabolic process
D	0007165	biological_process	signal transduction
D	0008233	molecular_function	peptidase activity
D	0008236	molecular_function	serine-type peptidase activity
D	0016787	molecular_function	hydrolase activity
D	0030288	cellular_component	outer membrane-bounded periplasmic space
D	0030435	biological_process	sporulation resulting in formation of a cellular spore
D	0042277	molecular_function	peptide binding
D	0042802	molecular_function	identical protein binding
D	0042803	molecular_function	protein homodimerization activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Nucleophile => ECO:0000269|PubMed:24243021

Chain	Residue	Details
A	SER309
B	SER309
C	SER309
D	SER309

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site_id	SWS_FT_FI2
Number of Residues	8
Details	ACT_SITE: Charge relay system => ECO:0000269|PubMed:24243021

Chain	Residue	Details
A	LYS334
A	GLN338
B	LYS334
B	GLN338
C	LYS334
C	GLN338
D	LYS334
D	GLN338

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site_id	SWS_FT_FI3
Number of Residues	4
Details	SITE: Crucial for substrate binding and protease activation => ECO:0000269|PubMed:24243021

Chain	Residue	Details
A	ARG168
B	ARG168
C	ARG168
D	ARG168

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