4C1K
Crystal structure of pyrococcus furiosus 3-deoxy-D-arabino- heptulosonate 7-phosphate synthase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016832 | molecular_function | aldehyde-lyase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016832 | molecular_function | aldehyde-lyase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016832 | molecular_function | aldehyde-lyase activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016832 | molecular_function | aldehyde-lyase activity |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| E | 0009058 | biological_process | biosynthetic process |
| E | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| E | 0016740 | molecular_function | transferase activity |
| E | 0016832 | molecular_function | aldehyde-lyase activity |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| F | 0009058 | biological_process | biosynthetic process |
| F | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| F | 0016740 | molecular_function | transferase activity |
| F | 0016832 | molecular_function | aldehyde-lyase activity |
| F | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CO3 A 1263 |
| Chain | Residue |
| A | ALA114 |
| A | ARG115 |
| A | LYS136 |
| A | ARG166 |
| A | PEP1264 |
| A | HOH2027 |
| A | HOH2038 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PEP A 1264 |
| Chain | Residue |
| A | GLN111 |
| A | GLY113 |
| A | ALA114 |
| A | ARG115 |
| A | LYS136 |
| A | ARG166 |
| A | HIS201 |
| A | CO31263 |
| A | CD1265 |
| A | HOH2009 |
| A | HOH2027 |
| A | HOH2038 |
| A | ARG55 |
| A | LYS60 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CD A 1265 |
| Chain | Residue |
| A | CYS31 |
| A | HIS201 |
| A | GLU227 |
| A | ASP238 |
| A | PEP1264 |
| A | HOH2009 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE PEP B 1263 |
| Chain | Residue |
| B | ARG55 |
| B | LYS60 |
| B | GLN111 |
| B | GLY113 |
| B | ALA114 |
| B | ARG115 |
| B | LYS136 |
| B | ARG166 |
| B | HIS201 |
| B | CO31265 |
| B | HOH2026 |
| B | HOH2028 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD B 1264 |
| Chain | Residue |
| B | CYS31 |
| B | HIS201 |
| B | GLU227 |
| B | ASP238 |
| B | HOH2003 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CO3 B 1265 |
| Chain | Residue |
| B | GLY113 |
| B | ALA114 |
| B | ARG115 |
| B | LYS136 |
| B | ARG166 |
| B | PEP1263 |
| B | HOH2026 |
| site_id | AC7 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE PEP C 1263 |
| Chain | Residue |
| C | ARG55 |
| C | LYS60 |
| C | GLN111 |
| C | GLY113 |
| C | ALA114 |
| C | ARG115 |
| C | LYS136 |
| C | ARG166 |
| C | HIS201 |
| C | CO31264 |
| C | HOH2005 |
| C | HOH2029 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CO3 C 1264 |
| Chain | Residue |
| C | GLY113 |
| C | ALA114 |
| C | ARG115 |
| C | LYS136 |
| C | ARG166 |
| C | PEP1263 |
| C | HOH2029 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD C 1265 |
| Chain | Residue |
| C | CYS31 |
| C | HIS201 |
| C | GLU227 |
| C | ASP238 |
| C | HOH2005 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CO3 D 1263 |
| Chain | Residue |
| D | ALA114 |
| D | ARG115 |
| D | LYS136 |
| D | ARG166 |
| D | HIS201 |
| D | PEP1264 |
| D | HOH2049 |
| site_id | BC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PEP D 1264 |
| Chain | Residue |
| D | ARG55 |
| D | LYS60 |
| D | PRO61 |
| D | GLU93 |
| D | GLN111 |
| D | GLY113 |
| D | ALA114 |
| D | ARG115 |
| D | LYS136 |
| D | ARG166 |
| D | HIS201 |
| D | CO31263 |
| D | HOH2019 |
| D | HOH2049 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD D 1265 |
| Chain | Residue |
| D | ASP238 |
| D | HOH2019 |
| D | CYS31 |
| D | HIS201 |
| D | GLU227 |
| site_id | BC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 2PE E 1265 |
| Chain | Residue |
| D | MET1 |
| D | LYS2 |
| D | TYR3 |
| D | SER4 |
| D | GLU6 |
| D | TYR148 |
| E | MET1 |
| E | SER4 |
| E | GLU6 |
| E | HOH2083 |
| E | HOH2084 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD E 1266 |
| Chain | Residue |
| E | CYS31 |
| E | HIS201 |
| E | GLU227 |
| E | ASP238 |
| E | PEP1264 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL F 1263 |
| Chain | Residue |
| F | LYS136 |
| F | ARG166 |
| F | HIS201 |
| F | PEP1264 |
| site_id | BC7 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PEP F 1264 |
| Chain | Residue |
| F | ARG55 |
| F | LYS60 |
| F | GLU93 |
| F | GLN111 |
| F | GLY113 |
| F | ALA114 |
| F | ARG115 |
| F | LYS136 |
| F | ARG166 |
| F | HIS201 |
| F | CL1263 |
| F | CD1265 |
| F | HOH2006 |
| F | HOH2014 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CD F 1265 |
| Chain | Residue |
| F | CYS31 |
| F | HIS201 |
| F | GLU227 |
| F | ASP238 |
| F | PEP1264 |
| F | HOH2006 |
| site_id | BC9 |
| Number of Residues | 11 |
| Details | Binding site for residues CL E1263 and PEP E1264 |
| Chain | Residue |
| E | ARG55 |
| E | LYS60 |
| E | GLN111 |
| E | GLY113 |
| E | ALA114 |
| E | ARG115 |
| E | LYS136 |
| E | ARG166 |
| E | HIS201 |
| E | CD1266 |
| E | HOH2036 |
