4C0J

Crystal structure of Drosophila Miro EF hand and cGTPase domains in the apo state (Apo-MiroS)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003924	molecular_function	GTPase activity
A	0005509	molecular_function	calcium ion binding
A	0005525	molecular_function	GTP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 1610

Chain	Residue
A	GLY456
A	GLY458
A	LYS459
A	THR460
A	HOH2043

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 1611

Chain	Residue
A	HOH2059
A	ARG240
A	ARG241
A	HIS508
A	ARG533

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 1612

Chain	Residue
A	LYS375
A	LYS477
A	GLU478
A	PHE479
A	THR481

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 1613

Chain	Residue
A	ILE401
A	LYS448
A	ARG502
A	HOH2047

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA A 1614

Chain	Residue
A	ASP223
A	ASP225
A	ASP227
A	LEU229
A	ASN231
A	GLU234

---

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE HSE A 1615

Chain	Residue
A	PHE277
A	HIS281

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Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DIDGDNLLNdyEL

Chain	Residue	Details
A	ASP223-LEU235

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448

Chain	Residue	Details
A	ASP223
A	ASP225
A	ASP227
A	GLU234

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000305

Chain	Residue	Details
A	ASP343
A	ASP345
A	ASP347
A	GLU354

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	BINDING: BINDING => ECO:0000255

Chain	Residue	Details
A	GLY453
A	GLN491
A	THR558

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