4BX0
Crystal Structure of a Monomeric Variant of murine Chronophin (Pyridoxal Phosphate phosphatase)
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000287 | molecular_function | magnesium ion binding |
A | 0004721 | molecular_function | phosphoprotein phosphatase activity |
A | 0004722 | molecular_function | protein serine/threonine phosphatase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0005856 | cellular_component | cytoskeleton |
A | 0005886 | cellular_component | plasma membrane |
A | 0005911 | cellular_component | cell-cell junction |
A | 0006470 | biological_process | protein dephosphorylation |
A | 0007088 | biological_process | regulation of mitotic nuclear division |
A | 0015629 | cellular_component | actin cytoskeleton |
A | 0016311 | biological_process | dephosphorylation |
A | 0016787 | molecular_function | hydrolase activity |
A | 0016791 | molecular_function | phosphatase activity |
A | 0017018 | molecular_function | myosin phosphatase activity |
A | 0030027 | cellular_component | lamellipodium |
A | 0030496 | cellular_component | midbody |
A | 0030836 | biological_process | positive regulation of actin filament depolymerization |
A | 0031072 | molecular_function | heat shock protein binding |
A | 0031247 | biological_process | actin rod assembly |
A | 0031258 | cellular_component | lamellipodium membrane |
A | 0032154 | cellular_component | cleavage furrow |
A | 0032361 | biological_process | pyridoxal phosphate catabolic process |
A | 0032465 | biological_process | regulation of cytokinesis |
A | 0032587 | cellular_component | ruffle membrane |
A | 0033883 | molecular_function | pyridoxal phosphatase activity |
A | 0042803 | molecular_function | protein homodimerization activity |
A | 0042995 | cellular_component | cell projection |
A | 0046872 | molecular_function | metal ion binding |
A | 0070938 | cellular_component | contractile ring |
A | 0071318 | biological_process | cellular response to ATP |
A | 0098794 | cellular_component | postsynapse |
A | 0098978 | cellular_component | glutamatergic synapse |
A | 0099159 | biological_process | regulation of modification of postsynaptic structure |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE MG A 1291 |
Chain | Residue |
A | ASP25 |
A | ASP27 |
A | ASP234 |
A | HOH2033 |
A | HOH2034 |
A | HOH2036 |
site_id | AC2 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE GOL A 1292 |
Chain | Residue |
A | GLY183 |
A | SER184 |
A | ARG185 |
A | HOH2181 |
A | HOH2242 |
A | ALA48 |
A | GLY51 |
A | LYS52 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: Nucleophile => ECO:0000305|PubMed:24338687, ECO:0000305|PubMed:25783190, ECO:0007744|PDB:4BX2, ECO:0007744|PDB:5AES |
Chain | Residue | Details |
A | ASP25 |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | ACT_SITE: Proton donor => ECO:0000305|PubMed:24338687, ECO:0000305|PubMed:25783190, ECO:0007744|PDB:4BX2, ECO:0007744|PDB:5AES |
Chain | Residue | Details |
A | ASP27 |
site_id | SWS_FT_FI3 |
Number of Residues | 3 |
Details | BINDING: BINDING => ECO:0000269|PubMed:24338473, ECO:0000269|PubMed:24338687, ECO:0000269|PubMed:25783190, ECO:0007744|PDB:4BKM, ECO:0007744|PDB:4BX0, ECO:0007744|PDB:4BX2, ECO:0007744|PDB:4BX3, ECO:0007744|PDB:5AES |
Chain | Residue | Details |
A | ASP25 | |
A | ASP27 | |
A | ASP234 |
site_id | SWS_FT_FI4 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000269|PubMed:24338687, ECO:0000269|PubMed:25783190, ECO:0007744|PDB:4BX2, ECO:0007744|PDB:5AES |
Chain | Residue | Details |
A | SER58 | |
A | LYS209 |
site_id | SWS_FT_FI5 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000269|PubMed:25783190, ECO:0007744|PDB:5AES |
Chain | Residue | Details |
A | HIS178 |