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4BRQ

LEGIONELLA PNEUMOPHILA NTPDASE1 CRYSTAL FORM II, CLOSED, IN COMPLEX WITH TWO PHOSPHATES BOUND TO ACTIVE SITE MG AND PRODUCT AMP

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0016787molecular_functionhydrolase activity
A0046872molecular_functionmetal ion binding
B0000166molecular_functionnucleotide binding
B0016787molecular_functionhydrolase activity
B0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues17
DetailsBINDING SITE FOR RESIDUE AMP A 1396
ChainResidue
ATHR53
APO41398
AHOH2017
AHOH2018
AHOH2055
AHOH2147
AHOH2260
AHOH2310
AHOH2335
AARG56
ALYS80
AGLN231
AGLY299
AASN302
ALEU303
ATYR346
ATYR350

site_idAC2
Number of Residues9
DetailsBINDING SITE FOR RESIDUE MES A 1397
ChainResidue
AHIS224
ASER225
APHE226
AVAL275
AHIS276
AGLN281
AHOH2173
AHOH2336
BGLU267

site_idAC3
Number of Residues11
DetailsBINDING SITE FOR RESIDUE PO4 A 1398
ChainResidue
ASER52
ATHR53
AARG56
AGLY188
AGLY189
AAMP1396
APO41399
AMG1401
AHOH2005
AHOH2144
AHOH2338

site_idAC4
Number of Residues13
DetailsBINDING SITE FOR RESIDUE PO4 A 1399
ChainResidue
ATHR118
AALA119
AGLU159
AGLY188
AGLY189
AALA190
ASER191
AGLN193
APO41398
AMG1401
AHOH2004
AHOH2134
AHOH2144

site_idAC5
Number of Residues5
DetailsBINDING SITE FOR RESIDUE CL A 1400
ChainResidue
AASN240
AASP253
AHOH2209
BARG122
BGLY156

site_idAC6
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MG A 1401
ChainResidue
APO41398
APO41399
AHOH2004
AHOH2005
AHOH2134
AHOH2144

site_idAC7
Number of Residues17
DetailsBINDING SITE FOR RESIDUE AMP B 1396
ChainResidue
BTHR53
BARG56
BLYS80
BGLN231
BGLY299
BASN302
BLEU303
BTYR346
BTYR350
BPO41398
BHOH2016
BHOH2019
BHOH2020
BHOH2052
BHOH2137
BHOH2267
BHOH2286

site_idAC8
Number of Residues8
DetailsBINDING SITE FOR RESIDUE MES B 1397
ChainResidue
AGLU267
AHOH2191
BHIS224
BPHE226
BVAL275
BHIS276
BGLN281
BHOH2198

site_idAC9
Number of Residues12
DetailsBINDING SITE FOR RESIDUE PO4 B 1398
ChainResidue
BSER52
BTHR53
BARG56
BGLY188
BGLY189
BAMP1396
BPO41399
BMG1400
BHOH2006
BHOH2007
BHOH2134
BHOH2287

site_idBC1
Number of Residues12
DetailsBINDING SITE FOR RESIDUE PO4 B 1399
ChainResidue
BALA119
BGLU159
BGLY188
BGLY189
BALA190
BSER191
BGLN193
BPO41398
BMG1400
BHOH2006
BHOH2123
BTHR118

site_idBC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MG B 1400
ChainResidue
BPO41398
BPO41399
BHOH2006
BHOH2007
BHOH2123
BHOH2134

site_idBC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE CL B 1401
ChainResidue
AARG122
AHOH2088
BASN240
BASP253

site_idBC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG A 1402
ChainResidue
AHOH2122
AHOH2123
AHOH2339
AHOH2340
AHOH2341

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PDB entries from 2024-10-30

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