4BOG

The structure and super-organization of acetylcholine receptor-rapsyn complexes

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0004888	molecular_function	transmembrane signaling receptor activity
0	0005216	molecular_function	monoatomic ion channel activity
0	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
0	0006811	biological_process	monoatomic ion transport
0	0016020	cellular_component	membrane
0	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
0	0034220	biological_process	monoatomic ion transmembrane transport
0	0045211	cellular_component	postsynaptic membrane
1	0004888	molecular_function	transmembrane signaling receptor activity
1	0005216	molecular_function	monoatomic ion channel activity
1	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
1	0006811	biological_process	monoatomic ion transport
1	0016020	cellular_component	membrane
1	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
1	0034220	biological_process	monoatomic ion transmembrane transport
1	0045211	cellular_component	postsynaptic membrane
2	0004888	molecular_function	transmembrane signaling receptor activity
2	0005216	molecular_function	monoatomic ion channel activity
2	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
2	0006811	biological_process	monoatomic ion transport
2	0016020	cellular_component	membrane
2	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
2	0034220	biological_process	monoatomic ion transmembrane transport
2	0045211	cellular_component	postsynaptic membrane
3	0004888	molecular_function	transmembrane signaling receptor activity
3	0005216	molecular_function	monoatomic ion channel activity
3	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
3	0006811	biological_process	monoatomic ion transport
3	0016020	cellular_component	membrane
3	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
3	0034220	biological_process	monoatomic ion transmembrane transport
3	0045211	cellular_component	postsynaptic membrane
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0045211	cellular_component	postsynaptic membrane
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
B	0006811	biological_process	monoatomic ion transport
B	0016020	cellular_component	membrane
B	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0045211	cellular_component	postsynaptic membrane
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
C	0006811	biological_process	monoatomic ion transport
C	0016020	cellular_component	membrane
C	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
C	0034220	biological_process	monoatomic ion transmembrane transport
C	0045211	cellular_component	postsynaptic membrane
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
D	0006811	biological_process	monoatomic ion transport
D	0016020	cellular_component	membrane
D	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
D	0034220	biological_process	monoatomic ion transmembrane transport
D	0045211	cellular_component	postsynaptic membrane
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0005216	molecular_function	monoatomic ion channel activity
E	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
E	0006811	biological_process	monoatomic ion transport
E	0016020	cellular_component	membrane
E	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
E	0034220	biological_process	monoatomic ion transmembrane transport
E	0045211	cellular_component	postsynaptic membrane
F	0004888	molecular_function	transmembrane signaling receptor activity
F	0005216	molecular_function	monoatomic ion channel activity
F	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
F	0006811	biological_process	monoatomic ion transport
F	0016020	cellular_component	membrane
F	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
F	0034220	biological_process	monoatomic ion transmembrane transport
F	0045211	cellular_component	postsynaptic membrane
G	0004888	molecular_function	transmembrane signaling receptor activity
G	0005216	molecular_function	monoatomic ion channel activity
G	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
G	0006811	biological_process	monoatomic ion transport
G	0016020	cellular_component	membrane
G	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
G	0034220	biological_process	monoatomic ion transmembrane transport
G	0045211	cellular_component	postsynaptic membrane
H	0004888	molecular_function	transmembrane signaling receptor activity
H	0005216	molecular_function	monoatomic ion channel activity
H	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
H	0006811	biological_process	monoatomic ion transport
H	0016020	cellular_component	membrane
H	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
H	0034220	biological_process	monoatomic ion transmembrane transport
H	0045211	cellular_component	postsynaptic membrane
I	0004888	molecular_function	transmembrane signaling receptor activity
I	0005216	molecular_function	monoatomic ion channel activity
I	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
I	0006811	biological_process	monoatomic ion transport
I	0016020	cellular_component	membrane
I	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
I	0034220	biological_process	monoatomic ion transmembrane transport
I	0045211	cellular_component	postsynaptic membrane
J	0004888	molecular_function	transmembrane signaling receptor activity
J	0005216	molecular_function	monoatomic ion channel activity
J	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
J	0006811	biological_process	monoatomic ion transport
J	0016020	cellular_component	membrane
J	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
J	0034220	biological_process	monoatomic ion transmembrane transport
J	0045211	cellular_component	postsynaptic membrane
K	0004888	molecular_function	transmembrane signaling receptor activity
K	0005216	molecular_function	monoatomic ion channel activity
K	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
K	0006811	biological_process	monoatomic ion transport
K	0016020	cellular_component	membrane
K	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
K	0034220	biological_process	monoatomic ion transmembrane transport
K	0045211	cellular_component	postsynaptic membrane
L	0004888	molecular_function	transmembrane signaling receptor activity
L	0005216	molecular_function	monoatomic ion channel activity
L	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
L	0006811	biological_process	monoatomic ion transport
L	0016020	cellular_component	membrane
L	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
L	0034220	biological_process	monoatomic ion transmembrane transport
L	0045211	cellular_component	postsynaptic membrane
M	0004888	molecular_function	transmembrane signaling receptor activity
M	0005216	molecular_function	monoatomic ion channel activity
M	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
M	0006811	biological_process	monoatomic ion transport
M	0016020	cellular_component	membrane
M	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
M	0034220	biological_process	monoatomic ion transmembrane transport
M	0045211	cellular_component	postsynaptic membrane
N	0004888	molecular_function	transmembrane signaling receptor activity
N	0005216	molecular_function	monoatomic ion channel activity
N	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
N	0006811	biological_process	monoatomic ion transport
N	0016020	cellular_component	membrane
N	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
N	0034220	biological_process	monoatomic ion transmembrane transport
N	0045211	cellular_component	postsynaptic membrane
O	0004888	molecular_function	transmembrane signaling receptor activity
O	0005216	molecular_function	monoatomic ion channel activity
O	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
O	0006811	biological_process	monoatomic ion transport
O	0016020	cellular_component	membrane
O	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
O	0034220	biological_process	monoatomic ion transmembrane transport
O	0045211	cellular_component	postsynaptic membrane
P	0004888	molecular_function	transmembrane signaling receptor activity
P	0005216	molecular_function	monoatomic ion channel activity
P	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
P	0006811	biological_process	monoatomic ion transport
P	0016020	cellular_component	membrane
P	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
P	0034220	biological_process	monoatomic ion transmembrane transport
P	0045211	cellular_component	postsynaptic membrane
Q	0004888	molecular_function	transmembrane signaling receptor activity
Q	0005216	molecular_function	monoatomic ion channel activity
Q	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
Q	0006811	biological_process	monoatomic ion transport
Q	0016020	cellular_component	membrane
Q	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
Q	0034220	biological_process	monoatomic ion transmembrane transport
Q	0045211	cellular_component	postsynaptic membrane
R	0004888	molecular_function	transmembrane signaling receptor activity
R	0005216	molecular_function	monoatomic ion channel activity
R	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
R	0006811	biological_process	monoatomic ion transport
R	0016020	cellular_component	membrane
R	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
R	0034220	biological_process	monoatomic ion transmembrane transport
R	0045211	cellular_component	postsynaptic membrane
S	0004888	molecular_function	transmembrane signaling receptor activity
S	0005216	molecular_function	monoatomic ion channel activity
S	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
S	0006811	biological_process	monoatomic ion transport
S	0016020	cellular_component	membrane
S	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
S	0034220	biological_process	monoatomic ion transmembrane transport
S	0045211	cellular_component	postsynaptic membrane
T	0004888	molecular_function	transmembrane signaling receptor activity
T	0005216	molecular_function	monoatomic ion channel activity
T	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
T	0006811	biological_process	monoatomic ion transport
T	0016020	cellular_component	membrane
T	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
T	0034220	biological_process	monoatomic ion transmembrane transport
T	0045211	cellular_component	postsynaptic membrane
U	0004888	molecular_function	transmembrane signaling receptor activity
U	0005216	molecular_function	monoatomic ion channel activity
U	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
U	0006811	biological_process	monoatomic ion transport
U	0016020	cellular_component	membrane
U	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
U	0034220	biological_process	monoatomic ion transmembrane transport
U	0045211	cellular_component	postsynaptic membrane
V	0004888	molecular_function	transmembrane signaling receptor activity
V	0005216	molecular_function	monoatomic ion channel activity
V	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
V	0006811	biological_process	monoatomic ion transport
V	0016020	cellular_component	membrane
V	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
V	0034220	biological_process	monoatomic ion transmembrane transport
V	0045211	cellular_component	postsynaptic membrane
W	0004888	molecular_function	transmembrane signaling receptor activity
W	0005216	molecular_function	monoatomic ion channel activity
W	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
W	0006811	biological_process	monoatomic ion transport
W	0016020	cellular_component	membrane
W	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
W	0034220	biological_process	monoatomic ion transmembrane transport
W	0045211	cellular_component	postsynaptic membrane
X	0004888	molecular_function	transmembrane signaling receptor activity
X	0005216	molecular_function	monoatomic ion channel activity
X	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
X	0006811	biological_process	monoatomic ion transport
X	0016020	cellular_component	membrane
X	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
X	0034220	biological_process	monoatomic ion transmembrane transport
X	0045211	cellular_component	postsynaptic membrane
Y	0004888	molecular_function	transmembrane signaling receptor activity
Y	0005216	molecular_function	monoatomic ion channel activity
Y	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
Y	0006811	biological_process	monoatomic ion transport
Y	0016020	cellular_component	membrane
Y	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
Y	0034220	biological_process	monoatomic ion transmembrane transport
Y	0045211	cellular_component	postsynaptic membrane
Z	0004888	molecular_function	transmembrane signaling receptor activity
Z	0005216	molecular_function	monoatomic ion channel activity
Z	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
Z	0006811	biological_process	monoatomic ion transport
Z	0016020	cellular_component	membrane
Z	0022848	molecular_function	acetylcholine-gated monoatomic cation-selective channel activity
Z	0034220	biological_process	monoatomic ion transmembrane transport
Z	0045211	cellular_component	postsynaptic membrane

Functional Information from PROSITE/UniProt

site_id	PS00236
Number of Residues	15
Details	NEUROTR_ION_CHANNEL Neurotransmitter-gated ion-channels signature. CpIaVtyFPfDwqnC

Chain	Residue	Details
Y	CYS127-CYS141
W	CYS130-CYS144
X	CYS128-CYS142
0	CYS128-CYS142

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI2
Number of Residues	2508
Details	Topological domain: {"description":"Extracellular"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	948
Details	Transmembrane: {"description":"Helical"}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	12
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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