Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004175 | molecular_function | endopeptidase activity |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0016485 | biological_process | protein processing |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004175 | molecular_function | endopeptidase activity |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0006508 | biological_process | proteolysis |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0008236 | molecular_function | serine-type peptidase activity |
| B | 0016485 | biological_process | protein processing |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0046872 | molecular_function | metal ion binding |
| I | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
| J | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 600 |
| Chain | Residue |
| A | GLU70 |
| A | ASP72 |
| A | VAL75 |
| A | GLU77 |
| A | GLU80 |
| A | HOH2088 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 601 |
| Chain | Residue |
| A | GLU231 |
| A | HOH2175 |
| A | HOH2176 |
| A | ASP165 |
| A | ASP178 |
| A | MET180 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 600 |
| Chain | Residue |
| B | GLU70 |
| B | ASP72 |
| B | VAL75 |
| B | GLU77 |
| B | GLU80 |
| B | HOH2059 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA B 601 |
| Chain | Residue |
| B | ASP165 |
| B | ASP178 |
| B | MET180 |
| B | GLU231 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 I 701 |
| Chain | Residue |
| I | PHE4 |
| I | ARG42 |
| I | HOH2005 |
| I | HOH2053 |
| I | HOH2065 |
| I | HOH2066 |
| I | HOH2067 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 J 701 |
| Chain | Residue |
| A | HOH2116 |
| J | GLU7 |
| J | LYS41 |
| J | ARG42 |
| J | HOH2008 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. ITAGHC |
| Chain | Residue | Details |
| A | ILE53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPLA |
| Chain | Residue | Details |
| A | ASP189-ALA200 | |
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. AASDTGSTYLAG |
| Chain | Residue | Details |
| A | ALA200-GLY211 | |
| site_id | PS00280 |
| Number of Residues | 19 |
| Details | BPTI_KUNITZ_1 Pancreatic trypsin inhibitor (Kunitz) family signature. FvyGGCrakrnnFksaedC |
| Chain | Residue | Details |
| I | PHE33-CYS51 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI3 |
| Number of Residues | 100 |
| Details | Domain: {"description":"BPTI/Kunitz inhibitor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00031","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Reactive bond for trypsin"} |
