4BNE

Pacsin2 Interacts with Membranes and Actin-Filaments

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005543	molecular_function	phospholipid binding
A	0005737	cellular_component	cytoplasm
A	0005768	cellular_component	endosome
A	0005769	cellular_component	early endosome
A	0005829	cellular_component	cytosol
A	0005856	cellular_component	cytoskeleton
A	0005886	cellular_component	plasma membrane
A	0005901	cellular_component	caveola
A	0005925	cellular_component	focal adhesion
A	0006897	biological_process	endocytosis
A	0007010	biological_process	cytoskeleton organization
A	0008092	molecular_function	cytoskeletal protein binding
A	0008289	molecular_function	lipid binding
A	0030036	biological_process	actin cytoskeleton organization
A	0030100	biological_process	regulation of endocytosis
A	0030659	cellular_component	cytoplasmic vesicle membrane
A	0031410	cellular_component	cytoplasmic vesicle
A	0032587	cellular_component	ruffle membrane
A	0042995	cellular_component	cell projection
A	0045806	biological_process	negative regulation of endocytosis
A	0055038	cellular_component	recycling endosome membrane
A	0070300	molecular_function	phosphatidic acid binding
A	0070836	biological_process	caveola assembly
A	0097320	biological_process	plasma membrane tubulation
B	0005543	molecular_function	phospholipid binding
B	0005737	cellular_component	cytoplasm
B	0005768	cellular_component	endosome
B	0005769	cellular_component	early endosome
B	0005829	cellular_component	cytosol
B	0005856	cellular_component	cytoskeleton
B	0005886	cellular_component	plasma membrane
B	0005901	cellular_component	caveola
B	0005925	cellular_component	focal adhesion
B	0006897	biological_process	endocytosis
B	0007010	biological_process	cytoskeleton organization
B	0008092	molecular_function	cytoskeletal protein binding
B	0008289	molecular_function	lipid binding
B	0030036	biological_process	actin cytoskeleton organization
B	0030100	biological_process	regulation of endocytosis
B	0030659	cellular_component	cytoplasmic vesicle membrane
B	0031410	cellular_component	cytoplasmic vesicle
B	0032587	cellular_component	ruffle membrane
B	0042995	cellular_component	cell projection
B	0045806	biological_process	negative regulation of endocytosis
B	0055038	cellular_component	recycling endosome membrane
B	0070300	molecular_function	phosphatidic acid binding
B	0070836	biological_process	caveola assembly
B	0097320	biological_process	plasma membrane tubulation

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 1305

Chain	Residue
A	GLN234
A	ARG284
A	HOH2106
B	ARG287

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 1306

Chain	Residue
A	GLN123
A	MET124
B	LYS150

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 1304

Chain	Residue
B	MET124
B	HOH2070
A	LYS150
B	GLN123

---

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 1307

Chain	Residue
A	LYS275
B	ARG245

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site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B 1305

Chain	Residue
A	TRP115
A	LYS239
A	ASP278
A	HOH2087
B	ARG242

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site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 1306

Chain	Residue
B	ARG139
B	LYS143

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site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SO4 A 1308

Chain	Residue
A	ARG139

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site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PGE A 1309

Chain	Residue
A	GLU130
A	GLN232

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site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PGE B 1307

Chain	Residue
B	GLU130
B	GLU133
B	ALA134
B	GLN232
B	HOH2044

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	498
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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