4BMX

Native structure of futalosine hydrolase of Helicobacter pylori strain 26695

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0005829	cellular_component	cytosol
A	0008652	biological_process	amino acid biosynthetic process
A	0008782	molecular_function	adenosylhomocysteine nucleosidase activity
A	0008930	molecular_function	methylthioadenosine nucleosidase activity
A	0009086	biological_process	methionine biosynthetic process
A	0009116	biological_process	nucleoside metabolic process
A	0009164	biological_process	nucleoside catabolic process
A	0009234	biological_process	menaquinone biosynthetic process
A	0016787	molecular_function	hydrolase activity
A	0019284	biological_process	L-methionine salvage from S-adenosylmethionine
A	0019509	biological_process	L-methionine salvage from methylthioadenosine
A	0102246	molecular_function	6-amino-6-deoxyfutalosine hydrolase activity
B	0003824	molecular_function	catalytic activity
B	0005829	cellular_component	cytosol
B	0008652	biological_process	amino acid biosynthetic process
B	0008782	molecular_function	adenosylhomocysteine nucleosidase activity
B	0008930	molecular_function	methylthioadenosine nucleosidase activity
B	0009086	biological_process	methionine biosynthetic process
B	0009116	biological_process	nucleoside metabolic process
B	0009164	biological_process	nucleoside catabolic process
B	0009234	biological_process	menaquinone biosynthetic process
B	0016787	molecular_function	hydrolase activity
B	0019284	biological_process	L-methionine salvage from S-adenosylmethionine
B	0019509	biological_process	L-methionine salvage from methylthioadenosine
B	0102246	molecular_function	6-amino-6-deoxyfutalosine hydrolase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE ADE B 1232

Chain	Residue
B	ALA80
B	ALA201
B	TRS1233
B	GLY81
B	PHE154
B	VAL155
B	VAL173
B	GLU174
B	MET175
B	SER198
B	ASP199

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site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE TRS B 1233

Chain	Residue
B	MET1
B	ALA10
B	MET11
B	GLU14
B	VAL79
B	GLU174
B	MET175
B	GLU176
B	ARG195
B	PHE209
B	ADE1232

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE TRS A 1232

Chain	Residue
A	SER125
A	GLU126
A	SER127

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Proton acceptor => ECO:0000250

Chain	Residue	Details
A	GLU14
B	GLU14

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site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: Proton donor => ECO:0000305

Chain	Residue	Details
A	ASP199
B	ASP199

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site_id	SWS_FT_FI3
Number of Residues	6
Details	BINDING:

Chain	Residue	Details
A	GLY81
A	VAL155
A	MET175
B	GLY81
B	VAL155
B	MET175

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