Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4BMJ

Structure of the UBZ1and2 tandem of the ubiquitin-binding adaptor protein TAX1BP1

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 101

Chain	Residue
A	CYS10
A	CYS13
A	HIS29
A	HIS33

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 102

Chain	Residue
A	CYS37
A	CYS40
A	HIS56
A	HIS60

site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 103

Chain	Residue
A	ARG55

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 101

Chain	Residue
B	CYS10
B	CYS13
B	HIS29
B	HIS33

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 102

Chain	Residue
B	CYS37
B	CYS40
B	HIS56
B	HIS60

site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL B 103

Chain	Residue
B	ARG55

site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL B 104

Chain	Residue
B	HIS60

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 101

Chain	Residue
C	CYS10
C	CYS13
C	HIS29
C	HIS33

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 102

Chain	Residue
C	CYS37
C	CYS40
C	HIS56
C	HIS60

site_id	BC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL C 103

Chain	Residue
C	ARG55

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 101

Chain	Residue
D	CYS10
D	CYS13
D	HIS29
D	HIS33

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 102

Chain	Residue
D	CYS37
D	CYS40
D	HIS56
D	HIS60

site_id	BC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL D 103

Chain	Residue
D	ARG55

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN E 101

Chain	Residue
E	CYS10
E	CYS13
E	HIS29
E	HIS33

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN E 102

Chain	Residue
E	CYS37
E	CYS40
E	HIS56
E	HIS60

site_id	BC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL E 103

Chain	Residue
E	GLN51
E	ARG55
E	HOH2004

site_id	BC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN F 101

Chain	Residue
F	CYS10
F	CYS13
F	HIS29
F	HIS33

site_id	BC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN F 102

Chain	Residue
F	CYS37
F	CYS40
F	HIS56
F	HIS60

site_id	CC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL F 103

Chain	Residue
F	ARG55

site_id	CC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN G 101

Chain	Residue
G	CYS10
G	CYS13
G	HIS29
G	HIS33

site_id	CC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN G 102

Chain	Residue
G	CYS37
G	CYS40
G	HIS56
G	HIS60

site_id	CC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL G 103

Chain	Residue
F	HOH2003
G	ARG55

site_id	CC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN H 101

Chain	Residue
H	CYS10
H	CYS13
H	HIS29
H	HIS33

site_id	CC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN H 102

Chain	Residue
H	CYS37
H	CYS40
H	HIS56
H	HIS60

site_id	CC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL H 103

Chain	Residue
H	ARG55

site_id	CC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN I 101

Chain	Residue
I	CYS10
I	CYS13
I	HIS29
I	HIS33

site_id	CC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN I 102

Chain	Residue
I	CYS37
I	CYS40
I	HIS56
I	HIS60

site_id	DC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL I 103

Chain	Residue
I	ARG55

site_id	DC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN J 101

Chain	Residue
J	CYS10
J	CYS13
J	HIS29
J	HIS33

site_id	DC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN J 102

Chain	Residue
J	CYS37
J	CYS40
J	HIS56
J	HIS60

site_id	DC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL J 103

Chain	Residue
I	HOH2007
J	GLN51
J	HOH2007

site_id	DC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN K 101

Chain	Residue
K	HIS33
K	CYS10
K	CYS13
K	HIS29

site_id	DC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN K 102

Chain	Residue
K	CYS37
K	CYS40
K	HIS56
K	HIS60

site_id	DC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL K 103

Chain	Residue
K	ARG55

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	286
Details	ZN_FING: UBZ1-type 1 => ECO:0000255\|PROSITE-ProRule:PRU01253

Chain	Residue	Details
A	HIS7-HIS33
J	HIS7-HIS33
K	HIS7-HIS33
B	HIS7-HIS33
C	HIS7-HIS33
D	HIS7-HIS33
E	HIS7-HIS33
F	HIS7-HIS33
G	HIS7-HIS33
H	HIS7-HIS33
I	HIS7-HIS33

site_id	SWS_FT_FI2
Number of Residues	286
Details	ZN_FING: UBZ1-type 2 => ECO:0000255\|PROSITE-ProRule:PRU01253

Chain	Residue	Details
A	TRP34-HIS60
J	TRP34-HIS60
K	TRP34-HIS60
B	TRP34-HIS60
C	TRP34-HIS60
D	TRP34-HIS60
E	TRP34-HIS60
F	TRP34-HIS60
G	TRP34-HIS60
H	TRP34-HIS60
I	TRP34-HIS60

site_id	SWS_FT_FI3
Number of Residues	88
Details	BINDING: BINDING => ECO:0000255\|PROSITE-ProRule:PRU01253

Chain	Residue	Details
A	CYS10
B	CYS13
B	HIS29
B	HIS33
B	CYS37
B	CYS40
B	HIS56
B	HIS60
C	CYS10
C	CYS13
C	HIS29
A	CYS13
C	HIS33
C	CYS37
C	CYS40
C	HIS56
C	HIS60
D	CYS10
D	CYS13
D	HIS29
D	HIS33
D	CYS37
A	HIS29
D	CYS40
D	HIS56
D	HIS60
E	CYS10
E	CYS13
E	HIS29
E	HIS33
E	CYS37
E	CYS40
E	HIS56
A	HIS33
E	HIS60
F	CYS10
F	CYS13
F	HIS29
F	HIS33
F	CYS37
F	CYS40
F	HIS56
F	HIS60
G	CYS10
A	CYS37
G	CYS13
G	HIS29
G	HIS33
G	CYS37
G	CYS40
G	HIS56
G	HIS60
H	CYS10
H	CYS13
H	HIS29
A	CYS40
H	HIS33
H	CYS37
H	CYS40
H	HIS56
H	HIS60
I	CYS10
I	CYS13
I	HIS29
I	HIS33
I	CYS37
A	HIS56
I	CYS40
I	HIS56
I	HIS60
J	CYS10
J	CYS13
J	HIS29
J	HIS33
J	CYS37
J	CYS40
J	HIS56
A	HIS60
J	HIS60
K	CYS10
K	CYS13
K	HIS29
K	HIS33
K	CYS37
K	CYS40
K	HIS56
K	HIS60
B	CYS10

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)