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4BM4

CRYSTAL STRUCTURE OF MANGANESE PEROXIDASE 4 FROM PLEUROTUS OSTREATUS - CRYSTAL FORM IV

Functional Information from GO Data
ChainGOidnamespacecontents
A0000302biological_processresponse to reactive oxygen species
A0004601molecular_functionperoxidase activity
A0005576cellular_componentextracellular region
A0006979biological_processresponse to oxidative stress
A0020037molecular_functionheme binding
A0034599biological_processcellular response to oxidative stress
A0042744biological_processhydrogen peroxide catabolic process
A0046872molecular_functionmetal ion binding
A0098869biological_processcellular oxidant detoxification
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE CA A 401
ChainResidue
AASP49
AGLY67
AASP69
ASER71
AHOH2024
AHOH2029

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE CA A 402
ChainResidue
AASP199
AASP201
ASER177
AASP194
ATHR196

site_idAC3
Number of Residues27
DetailsBINDING SITE FOR RESIDUE HEM A 500
ChainResidue
AHIS40
AGLU41
ALEU43
AARG44
APHE47
APRO146
AGLU147
APRO148
ALEU172
ALEU173
ASER175
AHIS176
AALA179
AALA180
AGLN181
AASP182
ATHR183
AILE184
APHE193
ALEU235
AMET269
AHOH2021
AHOH2022
AHOH2025
AHOH2109
AHOH2142
AHOH2204

Functional Information from PROSITE/UniProt
site_idPS00435
Number of Residues11
DetailsPEROXIDASE_1 Peroxidases proximal heme-ligand signature. EVVALLASHSV
ChainResidueDetails
AGLU168-VAL178

site_idPS00436
Number of Residues12
DetailsPEROXIDASE_2 Peroxidases active site signature. VHesLRLtFHDA
ChainResidueDetails
AVAL39-ALA50

222415

PDB entries from 2024-07-10

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