4BIU
Crystal structure of CpxAHDC (orthorhombic form 1)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000155 | molecular_function | phosphorelay sensor kinase activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0016020 | cellular_component | membrane |
| A | 0016310 | biological_process | phosphorylation |
| A | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| B | 0000155 | molecular_function | phosphorelay sensor kinase activity |
| B | 0007165 | biological_process | signal transduction |
| B | 0016020 | cellular_component | membrane |
| B | 0016310 | biological_process | phosphorylation |
| B | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| C | 0000155 | molecular_function | phosphorelay sensor kinase activity |
| C | 0007165 | biological_process | signal transduction |
| C | 0016020 | cellular_component | membrane |
| C | 0016310 | biological_process | phosphorylation |
| C | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| D | 0000155 | molecular_function | phosphorelay sensor kinase activity |
| D | 0007165 | biological_process | signal transduction |
| D | 0016020 | cellular_component | membrane |
| D | 0016310 | biological_process | phosphorylation |
| D | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| E | 0000155 | molecular_function | phosphorelay sensor kinase activity |
| E | 0007165 | biological_process | signal transduction |
| E | 0016020 | cellular_component | membrane |
| E | 0016310 | biological_process | phosphorylation |
| E | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| F | 0000155 | molecular_function | phosphorelay sensor kinase activity |
| F | 0007165 | biological_process | signal transduction |
| F | 0016020 | cellular_component | membrane |
| F | 0016310 | biological_process | phosphorylation |
| F | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE ADP C 501 |
| Chain | Residue |
| C | ASN360 |
| C | LEU445 |
| C | ARG363 |
| C | TYR364 |
| C | ASP386 |
| C | PRO389 |
| C | VAL391 |
| C | ILE399 |
| C | GLY420 |
| C | LEU421 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE ADP E 501 |
| Chain | Residue |
| E | ASN360 |
| E | ARG363 |
| E | TYR364 |
| E | ASP386 |
| E | PRO389 |
| E | VAL391 |
| E | ILE399 |
| E | TYR404 |
| E | GLY418 |
| E | LEU419 |
| E | LEU445 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ADP F 501 |
| Chain | Residue |
| F | ASN360 |
| F | ARG363 |
| F | TYR364 |
| F | ASP386 |
| F | PRO389 |
| F | VAL391 |
| F | ILE399 |
| F | ARG405 |
| F | THR406 |
| F | ALA409 |
| F | THR417 |
| F | GLY420 |
| F | LEU421 |
| F | LEU445 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 F 1455 |
| Chain | Residue |
| C | PRO340 |
| C | TRP341 |
| F | GLY339 |
| F | PRO340 |
| F | TRP341 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1456 |
| Chain | Residue |
| D | GLY339 |
| D | PRO340 |
| D | TRP341 |
| E | GLY339 |
| E | PRO340 |
| E | TRP341 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1457 |
| Chain | Residue |
| D | ASN360 |
| D | ARG363 |
| D | TYR364 |
| D | GLY418 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | ACT_SITE: Nucleophile => ECO:0000269|PubMed:24492262 |
| Chain | Residue | Details |
| A | HIS248 | |
| B | HIS248 | |
| C | HIS248 | |
| D | HIS248 | |
| E | HIS248 | |
| F | HIS248 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 30 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:24492262 |
| Chain | Residue | Details |
| A | HIS248 | |
| B | GLY416 | |
| C | HIS248 | |
| C | ARG359 | |
| C | ASP386 | |
| C | ARG405 | |
| C | GLY416 | |
| D | HIS248 | |
| D | ARG359 | |
| D | ASP386 | |
| D | ARG405 | |
| A | ARG359 | |
| D | GLY416 | |
| E | HIS248 | |
| E | ARG359 | |
| E | ASP386 | |
| E | ARG405 | |
| E | GLY416 | |
| F | HIS248 | |
| F | ARG359 | |
| F | ASP386 | |
| F | ARG405 | |
| A | ASP386 | |
| F | GLY416 | |
| A | ARG405 | |
| A | GLY416 | |
| B | HIS248 | |
| B | ARG359 | |
| B | ASP386 | |
| B | ARG405 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | MOD_RES: Phosphohistidine; by autocatalysis => ECO:0000255|PROSITE-ProRule:PRU00107, ECO:0000305|PubMed:24492262, ECO:0000305|PubMed:9401031 |
| Chain | Residue | Details |
| A | HIS248 | |
| B | HIS248 | |
| C | HIS248 | |
| D | HIS248 | |
| E | HIS248 | |
| F | HIS248 |
