4BGU
1.50 A resolution structure of the malate dehydrogenase from Haloferax volcanii
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0006099 | biological_process | tricarboxylic acid cycle |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0019752 | biological_process | carboxylic acid metabolic process |
| A | 0030060 | molecular_function | L-malate dehydrogenase (NAD+) activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0006099 | biological_process | tricarboxylic acid cycle |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0019752 | biological_process | carboxylic acid metabolic process |
| B | 0030060 | molecular_function | L-malate dehydrogenase (NAD+) activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0006099 | biological_process | tricarboxylic acid cycle |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| C | 0019752 | biological_process | carboxylic acid metabolic process |
| C | 0030060 | molecular_function | L-malate dehydrogenase (NAD+) activity |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0006099 | biological_process | tricarboxylic acid cycle |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| D | 0019752 | biological_process | carboxylic acid metabolic process |
| D | 0030060 | molecular_function | L-malate dehydrogenase (NAD+) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K A 1305 |
| Chain | Residue |
| A | ASP28 |
| A | HOH2042 |
| A | HOH2052 |
| A | HOH2108 |
| C | ASP240 |
| C | HOH2358 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K A 1306 |
| Chain | Residue |
| A | HOH2220 |
| A | HOH2224 |
| A | HOH2249 |
| A | ASP101 |
| A | SER105 |
| A | THR133 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE K A 1307 |
| Chain | Residue |
| A | GLU109 |
| A | 1PE1342 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE K A 1308 |
| Chain | Residue |
| A | PGE1341 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K A 1309 |
| Chain | Residue |
| A | SER185 |
| A | HOH2141 |
| A | HOH2216 |
| A | HOH2352 |
| A | HOH2364 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K A 1310 |
| Chain | Residue |
| A | SER72 |
| A | GLY86 |
| A | ASP113 |
| A | HOH2145 |
| A | HOH2146 |
| A | HOH2150 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE K A 1312 |
| Chain | Residue |
| A | P331343 |
| A | HOH2514 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 1313 |
| Chain | Residue |
| A | HOH2290 |
| A | HOH2293 |
| A | HOH2387 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 1314 |
| Chain | Residue |
| A | VAL13 |
| A | HOH2084 |
| A | HOH2239 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 1315 |
| Chain | Residue |
| A | GLY191 |
| A | HOH2357 |
| D | TRP279 |
| D | HOH2269 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 1316 |
| Chain | Residue |
| A | PRO36 |
| A | LYS37 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 1317 |
| Chain | Residue |
| A | ASN121 |
| A | PRO122 |
| A | VAL123 |
| A | HIS176 |
| A | HOH2189 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 1318 |
| Chain | Residue |
| A | ARG89 |
| A | LYS295 |
| A | GLN299 |
| site_id | BC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 1319 |
| Chain | Residue |
| A | ARG89 |
| A | ASN121 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 1320 |
| Chain | Residue |
| A | ARG160 |
| A | GLU200 |
| A | HOH2306 |
| A | HOH2368 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 1321 |
| Chain | Residue |
| A | ARG152 |
| A | THR222 |
| A | HOH2333 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 1322 |
| Chain | Residue |
| A | ASN192 |
| A | PRO194 |
| A | HOH2355 |
| A | HOH2361 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 1323 |
| Chain | Residue |
| A | ASP135 |
| A | ARG136 |
| A | HOH2219 |
| A | HOH2232 |
| site_id | CC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 1324 |
| Chain | Residue |
| A | TYR131 |
| A | ARG138 |
| A | HOH2267 |
| site_id | CC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 1325 |
| Chain | Residue |
| A | ARG136 |
| A | ASP137 |
| A | HOH2272 |
| site_id | CC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 1326 |
| Chain | Residue |
| A | ASN20 |
| A | ARG24 |
| A | HOH2031 |
| B | HOH2083 |
| site_id | CC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 1328 |
| Chain | Residue |
| A | GLN223 |
| A | HOH2024 |
| B | GLN223 |
| B | HOH2018 |
| site_id | CC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 1329 |
| Chain | Residue |
| A | LYS186 |
| A | ASP280 |
| A | HOH2474 |
| D | ASN192 |
| D | ASP193 |
| site_id | CC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 1330 |
| Chain | Residue |
| A | GLY71 |
| A | TYR110 |
| A | ASN111 |
| A | 1PE1342 |
| A | HOH2179 |
| A | HOH2233 |
| site_id | CC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 1338 |
| Chain | Residue |
| A | GLN209 |
| A | HOH2392 |
| site_id | CC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 1339 |
| Chain | Residue |
| A | 1PE1342 |
| A | HOH2222 |
| site_id | CC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE TRS A 1340 |
| Chain | Residue |
| A | HOH2508 |
| A | HOH2509 |
| A | HOH2510 |
| A | HOH2511 |
| A | HOH2283 |
| A | HOH2285 |
| A | HOH2287 |
| A | HOH2328 |
| A | HOH2329 |
| site_id | DC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PGE A 1341 |
| Chain | Residue |
| A | TYR131 |
| A | GLU132 |
| A | ARG136 |
| A | K1308 |
| A | HOH2253 |
| A | HOH2257 |
| A | HOH2262 |
| site_id | DC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 1PE A 1342 |
| Chain | Residue |
| A | ALA108 |
| A | GLU109 |
| A | TYR110 |
| A | ASN111 |
| A | ASP178 |
| A | K1307 |
| A | CL1330 |
| A | CL1339 |
| site_id | DC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE P33 A 1343 |
| Chain | Residue |
| A | PHE255 |
| A | TYR257 |
| A | ASP290 |
| A | K1312 |
| D | ASP282 |
| D | ASP283 |
| D | HOH2391 |
| site_id | DC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE K B 1305 |
| Chain | Residue |
| B | ASP28 |
| B | HOH2035 |
| B | HOH2042 |
| B | HOH2044 |
| B | HOH2088 |
| D | ASP240 |
| D | HOH2346 |
| site_id | DC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K B 1306 |
| Chain | Residue |
| B | ASP101 |
| B | SER105 |
| B | THR133 |
| B | HOH2179 |
| B | HOH2208 |
| site_id | DC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE K B 1307 |
| Chain | Residue |
| B | GLU109 |
| B | 1PE1342 |
| site_id | DC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE K B 1308 |
| Chain | Residue |
| B | PGE1341 |
| site_id | DC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 1313 |
| Chain | Residue |
| B | HOH2241 |
| B | HOH2242 |
| B | HOH2333 |
| site_id | DC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 1314 |
| Chain | Residue |
| B | VAL13 |
| B | HOH2077 |
| B | HOH2197 |
| B | HOH2352 |
| site_id | EC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 1315 |
| Chain | Residue |
| B | HOH2304 |
| C | HOH2282 |
| site_id | EC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 1316 |
| Chain | Residue |
| B | PRO36 |
| B | LYS37 |
| site_id | EC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 1317 |
| Chain | Residue |
| B | ASN121 |
| B | PRO122 |
| B | VAL123 |
| B | HIS176 |
| B | HOH2151 |
| site_id | EC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 1318 |
| Chain | Residue |
| B | ARG89 |
| B | LYS295 |
| B | GLN299 |
| site_id | EC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 1319 |
| Chain | Residue |
| B | ARG89 |
| B | ASN121 |
| site_id | EC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 1320 |
| Chain | Residue |
| B | ARG160 |
| B | CL1332 |
| site_id | EC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 1321 |
| Chain | Residue |
| B | ARG152 |
| B | THR222 |
| B | HOH2236 |
| B | HOH2278 |
| site_id | EC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 1322 |
| Chain | Residue |
| B | ASN192 |
| B | HOH2109 |
| site_id | EC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 1323 |
| Chain | Residue |
| B | ASP135 |
| B | ARG136 |
| B | HOH2176 |
| site_id | FC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 1324 |
| Chain | Residue |
| B | TYR131 |
| B | ARG138 |
| B | HOH2223 |
| site_id | FC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 1325 |
| Chain | Residue |
| B | ASP113 |
| B | ARG136 |
| B | ASP137 |
| B | HOH2194 |
| site_id | FC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 1327 |
| Chain | Residue |
| B | ARG218 |
| B | HOH2347 |
| site_id | FC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 1332 |
| Chain | Residue |
| B | ALA195 |
| B | PHE196 |
| B | CL1320 |
| B | HOH2122 |
| site_id | FC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 1336 |
| Chain | Residue |
| B | LYS3 |
| B | ASP68 |
| B | HOH2007 |
| B | HOH2093 |
| B | HOH2106 |
| site_id | FC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 1337 |
| Chain | Residue |
| A | HOH2289 |
| B | GLN63 |
| B | HOH2075 |
| B | HOH2096 |
| site_id | FC7 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE TRS B 1340 |
| Chain | Residue |
| B | LYS166 |
| B | ASP169 |
| B | HOH2237 |
| B | HOH2238 |
| B | HOH2239 |
| B | HOH2265 |
| B | HOH2266 |
| B | HOH2273 |
| B | HOH2441 |
| B | HOH2442 |
| B | HOH2443 |
| B | HOH2444 |
| site_id | FC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PGE B 1341 |
| Chain | Residue |
| B | TYR131 |
| B | GLU132 |
| B | GLY134 |
| B | ASP135 |
| B | ARG136 |
| B | K1308 |
| B | HOH2221 |
| site_id | FC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE 1PE B 1342 |
| Chain | Residue |
| B | ALA108 |
| B | GLU109 |
| B | TYR110 |
| B | K1307 |
| site_id | GC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE K C 1305 |
| Chain | Residue |
| A | ASP240 |
| A | HOH2418 |
| A | HOH2421 |
| A | HOH2422 |
| C | ASP28 |
| C | HOH2042 |
| C | HOH2046 |
| site_id | GC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K C 1306 |
| Chain | Residue |
| C | ASP101 |
| C | SER105 |
| C | THR133 |
| C | HOH2175 |
| C | HOH2215 |
| site_id | GC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE K C 1307 |
| Chain | Residue |
| C | GLU109 |
| C | PG41342 |
| site_id | GC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE K C 1308 |
| Chain | Residue |
| C | PG41341 |
| C | HOH2223 |
| site_id | GC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE K C 1309 |
| Chain | Residue |
| B | HOH2115 |
| C | SER185 |
| C | HOH2301 |
| C | HOH2306 |
| site_id | GC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K C 1310 |
| Chain | Residue |
| C | SER72 |
| C | ASP113 |
| C | HOH2056 |
| C | HOH2122 |
| C | HOH2125 |
| C | HOH2128 |
| site_id | GC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K C 1311 |
| Chain | Residue |
| A | HOH2388 |
| A | HOH2389 |
| C | ASP301 |
| C | ILE303 |
| C | HOH2419 |
| C | HOH2422 |
| site_id | GC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C 1313 |
| Chain | Residue |
| C | HOH2253 |
| C | HOH2256 |
| C | HOH2326 |
| site_id | GC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL C 1314 |
| Chain | Residue |
| C | VAL13 |
| C | HOH2077 |
| C | HOH2204 |
| C | HOH2207 |
| site_id | HC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL C 1315 |
| Chain | Residue |
| B | HOH2271 |
| C | HOH2304 |
| site_id | HC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL C 1316 |
| Chain | Residue |
| C | PRO36 |
| C | LYS37 |
| site_id | HC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL C 1317 |
| Chain | Residue |
| C | ASN121 |
| C | PRO122 |
| C | VAL123 |
| C | HIS176 |
| C | HOH2152 |
| site_id | HC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C 1318 |
| Chain | Residue |
| C | ARG89 |
| C | LYS295 |
| C | GLN299 |
| site_id | HC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C 1319 |
| Chain | Residue |
| C | ARG83 |
| C | ARG89 |
| C | ASN121 |
| site_id | HC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C 1320 |
| Chain | Residue |
| C | ARG160 |
| C | GLU200 |
| C | HOH2309 |
| site_id | HC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL C 1321 |
| Chain | Residue |
| C | ARG152 |
| C | THR222 |
| C | HOH2245 |
| C | HOH2287 |
| site_id | HC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL C 1322 |
| Chain | Residue |
| B | HOH2170 |
| C | ASN192 |
| C | PRO194 |
| C | HOH2302 |
| site_id | HC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL C 1323 |
| Chain | Residue |
| C | ASP135 |
| C | ARG136 |
| C | HOH2172 |
| C | HOH2189 |
| site_id | IC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL C 1326 |
| Chain | Residue |
| C | ASN20 |
| C | ARG24 |
| C | HOH2031 |
| D | HOH2074 |
| site_id | IC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C 1327 |
| Chain | Residue |
| C | MET213 |
| C | ARG218 |
| C | CL1334 |
| site_id | IC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C 1329 |
| Chain | Residue |
| B | ASP193 |
| C | LYS186 |
| C | ASP280 |
| site_id | IC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL C 1334 |
| Chain | Residue |
| C | MET213 |
| C | ARG218 |
| C | CL1327 |
| C | HOH2135 |
| C | HOH2337 |
| site_id | IC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PG4 C 1341 |
| Chain | Residue |
| A | ASP102 |
| A | GLU109 |
| C | TYR131 |
| C | GLU132 |
| C | GLY134 |
| C | ASP135 |
| C | ARG136 |
| C | K1308 |
| C | HOH2223 |
| site_id | IC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PG4 C 1342 |
| Chain | Residue |
| C | ALA108 |
| C | GLU109 |
| C | TYR110 |
| C | ASN111 |
| C | ASP112 |
| C | K1307 |
| site_id | IC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K D 1305 |
| Chain | Residue |
| B | ASP240 |
| B | HOH2361 |
| B | HOH2362 |
| B | HOH2363 |
| D | ASP28 |
| D | HOH2031 |
| site_id | IC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE K D 1306 |
| Chain | Residue |
| D | ASP101 |
| D | SER105 |
| D | THR133 |
| D | HOH2070 |
| site_id | IC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE K D 1307 |
| Chain | Residue |
| D | GLU109 |
| site_id | JC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE K D 1308 |
| Chain | Residue |
| D | GLY134 |
| D | ASP135 |
| D | PGE1341 |
| D | HOH2216 |
| site_id | JC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K D 1309 |
| Chain | Residue |
| A | HOH2142 |
| D | SER185 |
| D | HOH2287 |
| D | HOH2289 |
| D | HOH2294 |
| site_id | JC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL D 1313 |
| Chain | Residue |
| D | VAL156 |
| D | HOH2243 |
| D | HOH2245 |
| D | HOH2315 |
| site_id | JC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL D 1314 |
| Chain | Residue |
| D | VAL13 |
| D | HOH2066 |
| D | HOH2135 |
| D | HOH2200 |
| site_id | JC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL D 1315 |
| Chain | Residue |
| A | HOH2326 |
| D | HOH2292 |
| site_id | JC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL D 1316 |
| Chain | Residue |
| D | PRO36 |
| D | LYS37 |
| site_id | JC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL D 1317 |
| Chain | Residue |
| D | ASN121 |
| D | PRO122 |
| D | VAL123 |
| D | HIS176 |
| D | HOH2149 |
| site_id | JC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL D 1318 |
| Chain | Residue |
| D | ARG89 |
| D | LYS295 |
| D | GLN299 |
| site_id | JC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL D 1319 |
| Chain | Residue |
| D | ARG83 |
| D | ARG89 |
| D | ASN121 |
| site_id | KC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL D 1320 |
| Chain | Residue |
| D | ARG160 |
| site_id | KC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL D 1321 |
| Chain | Residue |
| D | ARG152 |
| D | THR222 |
| D | HOH2240 |
| D | HOH2273 |
| D | HOH2336 |
| site_id | KC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL D 1322 |
| Chain | Residue |
| A | HOH2211 |
| D | ASN192 |
| D | HOH2290 |
| site_id | KC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL D 1323 |
| Chain | Residue |
| D | GLY134 |
| D | ASP135 |
| D | HOH2070 |
| D | HOH2177 |
| D | HOH2178 |
| site_id | KC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL D 1324 |
| Chain | Residue |
| D | TYR131 |
| D | ASP137 |
| D | ARG138 |
| D | HOH2228 |
| site_id | KC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL D 1325 |
| Chain | Residue |
| D | ASP113 |
| D | ARG136 |
| D | ASP137 |
| D | HOH2196 |
| site_id | KC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL D 1326 |
| Chain | Residue |
| C | HOH2092 |
| D | ASN20 |
| D | ARG24 |
| D | HOH2022 |
| site_id | KC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL D 1327 |
| Chain | Residue |
| D | ARG218 |
| D | HOH2331 |
| site_id | KC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL D 1328 |
| Chain | Residue |
| C | GLN223 |
| D | GLN223 |
| site_id | LC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL D 1330 |
| Chain | Residue |
| D | GLY71 |
| D | GLY71 |
| site_id | LC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL D 1331 |
| Chain | Residue |
| D | LEU205 |
| D | HOH2106 |
| D | HOH2121 |
| D | HOH2283 |
| site_id | LC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL D 1333 |
| Chain | Residue |
| D | HOH2366 |
| D | HOH2367 |
| site_id | LC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL D 1335 |
| Chain | Residue |
| C | TYR55 |
| D | ARG154 |
| D | THR171 |
| D | PRO246 |
| D | HOH2353 |
| site_id | LC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PGE D 1341 |
| Chain | Residue |
| D | TYR131 |
| D | GLU132 |
| D | GLY134 |
| D | ASP135 |
| D | ARG136 |
| D | K1308 |
| D | HOH2215 |
| D | HOH2427 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton acceptor => ECO:0000250|UniProtKB:P61889 |
| Chain | Residue | Details |
| A | HIS176 | |
| B | HIS176 | |
| C | HIS176 | |
| D | HIS176 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:O08349 |
| Chain | Residue | Details |
| A | GLY8 | |
| C | ASP34 | |
| C | ASN96 | |
| C | THR119 | |
| D | GLY8 | |
| D | ASP34 | |
| D | ASN96 | |
| D | THR119 | |
| A | ASP34 | |
| A | ASN96 | |
| A | THR119 | |
| B | GLY8 | |
| B | ASP34 | |
| B | ASN96 | |
| B | THR119 | |
| C | GLY8 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P61889 |
| Chain | Residue | Details |
| A | ARG83 | |
| C | ARG89 | |
| C | ASN121 | |
| C | ARG152 | |
| D | ARG83 | |
| D | ARG89 | |
| D | ASN121 | |
| D | ARG152 | |
| A | ARG89 | |
| A | ASN121 | |
| A | ARG152 | |
| B | ARG83 | |
| B | ARG89 | |
| B | ASN121 | |
| B | ARG152 | |
| C | ARG83 |
