Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016303 | molecular_function | 1-phosphatidylinositol-3-kinase activity |
| A | 0043491 | biological_process | phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| A | 0046854 | biological_process | phosphatidylinositol phosphate biosynthetic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016303 | molecular_function | 1-phosphatidylinositol-3-kinase activity |
| B | 0043491 | biological_process | phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| B | 0046854 | biological_process | phosphatidylinositol phosphate biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE J82 A 2000 |
| Chain | Residue |
| A | TYR772 |
| A | VAL848 |
| A | MET920 |
| A | ILE930 |
| A | ASP931 |
| A | HOH2019 |
| A | MET773 |
| A | PRO779 |
| A | TRP781 |
| A | ILE797 |
| A | LYS799 |
| A | TYR833 |
| A | GLU846 |
| A | VAL847 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE J82 B 2000 |
| Chain | Residue |
| B | TYR772 |
| B | MET773 |
| B | PRO779 |
| B | TRP781 |
| B | LYS799 |
| B | TYR833 |
| B | GLU846 |
| B | VAL847 |
| B | VAL848 |
| B | MET920 |
| B | PHE928 |
| B | ILE930 |
| B | ASP931 |
| B | HOH2033 |
Functional Information from PROSITE/UniProt
| site_id | PS00430 |
| Number of Residues | 99 |
| Details | TONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. gekldskigvligkglhefdalkdpevnefrrkmrkfseakiqslvglswidwlkhtyppehepsvlenledklyggklvvavhfensqdv........................FSFQVSPN |
| Chain | Residue | Details |
| A | GLY113-ASN211 | |
| site_id | PS00915 |
| Number of Residues | 15 |
| Details | PI3_4_KINASE_1 Phosphatidylinositol 3- and 4-kinases signature 1. FKng.DDLRQDmltlQ |
| Chain | Residue | Details |
| A | PHE798-GLN812 | |
| site_id | PS00916 |
| Number of Residues | 21 |
| Details | PI3_4_KINASE_2 Phosphatidylinositol 3- and 4-kinases signature 2. ScAgycVasYVLgIgDRHsdN |
| Chain | Residue | Details |
| A | SER898-ASN918 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Region: {"description":"G-loop","evidences":[{"source":"PROSITE-ProRule","id":"PRU00269","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Region: {"description":"Catalytic loop","evidences":[{"source":"PROSITE-ProRule","id":"PRU00269","evidenceCode":"ECO:0000255"}]} |
