4BEQ
Structure of Vibrio cholerae broad spectrum racemase double mutant R173A, N174A
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006522 | biological_process | alanine metabolic process |
| A | 0008784 | molecular_function | alanine racemase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0018111 | molecular_function | methionine racemase activity |
| A | 0018113 | molecular_function | lysine racemase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0030378 | molecular_function | serine racemase activity |
| A | 0030632 | biological_process | D-alanine biosynthetic process |
| A | 0042597 | cellular_component | periplasmic space |
| A | 0047661 | molecular_function | amino-acid racemase activity |
| A | 0047679 | molecular_function | arginine racemase activity |
| A | 0050157 | molecular_function | ornithine racemase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PLP A 1350 |
| Chain | Residue |
| A | LYS74 |
| A | HOH2264 |
| A | HOH2265 |
| A | HOH2299 |
| A | HOH2339 |
| A | HOH2397 |
| A | TYR78 |
| A | VAL120 |
| A | HIS204 |
| A | SER245 |
| A | ARG260 |
| A | GLY262 |
| A | GLY263 |
| A | HOH2167 |
Functional Information from PROSITE/UniProt
| site_id | PS00395 |
| Number of Residues | 11 |
| Details | ALANINE_RACEMASE Alanine racemase pyridoxal-phosphate attachment site. AImKADAYGNG |
| Chain | Residue | Details |
| A | ALA71-GLY81 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_02212","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_02212","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Specificity determinant that enlarges the space within the active site of Bsr compared to Alr, allowing the accomodation of a wider range of substrates","evidences":[{"source":"PubMed","id":"24419381","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"source":"HAMAP-Rule","id":"MF_02212","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24419381","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4BEQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4BEU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
