4BDW

The structure of the FnI-EGF tandem domain of coagulation factor XII in complex with Holmium

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE HO A 1086

Chain	Residue
A	ASP82
A	THR83
A	ALA85

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site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE HO A 1087

Chain	Residue
A	HOH2014
A	HOH2014
A	HOH2015
A	HOH2015
A	ALA85
A	ALA85
A	HOH2012
A	HOH2012
A	HOH2013
A	HOH2013

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site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 1088

Chain	Residue
A	LYS4
A	LYS4

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Functional Information from PROSITE/UniProt

site_id	PS00022
Number of Residues	12
Details	EGF_1 EGF-like domain signature 1. ChCpvGytGPfC

Chain	Residue	Details
A	CYS68-CYS79

---

site_id	PS01186
Number of Residues	12
Details	EGF_2 EGF-like domain signature 2. ChCpvGYtgpf....C

Chain	Residue	Details
A	CYS68-CYS79

---

site_id	PS01253
Number of Residues	36
Details	FN1_1 Fibronectin type-I domain signature. CfepqllrfFhkneiWyRteqaavar..CqCkgpdah...C

Chain	Residue	Details
A	CYS5-CYS40

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	40
Details	Domain: {"description":"Fibronectin type-I","evidences":[{"source":"PROSITE-ProRule","id":"PRU00478","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	36
Details	Domain: {"description":"EGF-like 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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