4BDM

Crystal structure of the GluK2 K531A LBD dimer in complex with kainate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0015276	molecular_function	ligand-gated monoatomic ion channel activity
A	0016020	cellular_component	membrane
B	0015276	molecular_function	ligand-gated monoatomic ion channel activity
B	0016020	cellular_component	membrane
C	0015276	molecular_function	ligand-gated monoatomic ion channel activity
C	0016020	cellular_component	membrane
D	0015276	molecular_function	ligand-gated monoatomic ion channel activity
D	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE KAI A 900

Chain	Residue
A	TYR488
A	GLU738
A	PRO516
A	ALA518
A	ARG523
A	VAL685
A	GLY688
A	ALA689
A	THR690
A	ASN721

---

site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE KAI B 900

Chain	Residue
B	GLU440
B	TYR488
B	PRO516
B	LEU517
B	ALA518
B	ARG523
B	VAL685
B	GLY688
B	ALA689
B	THR690
B	ASN721
B	GLU738

---

site_id	AC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE KAI C 900

Chain	Residue
C	GLU440
C	TYR488
C	PRO516
C	LEU517
C	ALA518
C	ARG523
C	GLY688
C	ALA689
C	THR690
C	ASN721
C	GLU738

---

site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE KAI D 900

Chain	Residue
D	TYR488
D	PRO516
D	ALA518
D	ARG523
D	GLY688
D	ALA689
D	THR690
D	ASN721
D	GLU738

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	BINDING: BINDING => ECO:0000269|PubMed:15721240, ECO:0000269|PubMed:17115050, ECO:0007744|PDB:1S50, ECO:0007744|PDB:1S7Y, ECO:0007744|PDB:2I0B, ECO:0007744|PDB:2I0C

Chain	Residue	Details
A	PRO516
B	ALA689
B	THR690
B	GLU738
C	PRO516
C	ALA518
C	ARG523
C	ALA689
C	THR690
C	GLU738
D	PRO516
A	ALA518
D	ALA518
D	ARG523
D	ALA689
D	THR690
D	GLU738
A	ARG523
A	ALA689
A	THR690
A	GLU738
B	PRO516
B	ALA518
B	ARG523

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN430
B	ASN430
C	ASN430
D	ASN430

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15677325, ECO:0000269|PubMed:8163463

Chain	Residue	Details
A	ASN751
B	ASN751
C	ASN751
D	ASN751

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