4BC2

Crystal structure of human D-xylulokinase in complex with D-xylulose and adenosine diphosphate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004856	molecular_function	D-xylulokinase activity
A	0005524	molecular_function	ATP binding
A	0005829	cellular_component	cytosol
A	0005975	biological_process	carbohydrate metabolic process
A	0005997	biological_process	xylulose metabolic process
A	0005998	biological_process	xylulose catabolic process
A	0006091	biological_process	generation of precursor metabolites and energy
A	0016301	molecular_function	kinase activity
A	0016740	molecular_function	transferase activity
A	0019640	biological_process	D-glucuronate catabolic process to D-xylulose 5-phosphate
A	0042732	biological_process	D-xylose metabolic process
A	0046835	biological_process	carbohydrate phosphorylation
B	0000166	molecular_function	nucleotide binding
B	0004856	molecular_function	D-xylulokinase activity
B	0005524	molecular_function	ATP binding
B	0005829	cellular_component	cytosol
B	0005975	biological_process	carbohydrate metabolic process
B	0005997	biological_process	xylulose metabolic process
B	0005998	biological_process	xylulose catabolic process
B	0006091	biological_process	generation of precursor metabolites and energy
B	0016301	molecular_function	kinase activity
B	0016740	molecular_function	transferase activity
B	0019640	biological_process	D-glucuronate catabolic process to D-xylulose 5-phosphate
B	0042732	biological_process	D-xylose metabolic process
B	0046835	biological_process	carbohydrate phosphorylation
C	0000166	molecular_function	nucleotide binding
C	0004856	molecular_function	D-xylulokinase activity
C	0005524	molecular_function	ATP binding
C	0005829	cellular_component	cytosol
C	0005975	biological_process	carbohydrate metabolic process
C	0005997	biological_process	xylulose metabolic process
C	0005998	biological_process	xylulose catabolic process
C	0006091	biological_process	generation of precursor metabolites and energy
C	0016301	molecular_function	kinase activity
C	0016740	molecular_function	transferase activity
C	0019640	biological_process	D-glucuronate catabolic process to D-xylulose 5-phosphate
C	0042732	biological_process	D-xylose metabolic process
C	0046835	biological_process	carbohydrate phosphorylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE ADP B 1533

Chain	Residue
B	SER340
B	TRP355
B	GLY441
B	ALA442
B	ASN445
B	HOH2178
B	HOH2180
B	HOH2284

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ADP A 1533

Chain	Residue
A	GLY441
A	ASN445
A	HOH2183
A	HOH2184
A	HOH2237
A	TRP355

---

site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE ADP C 1533

Chain	Residue
A	HOH2040
C	LEU299
C	SER340
C	GLU344
C	TRP355
C	GLY441
C	ALA442
C	ASN445
C	HOH2138
C	HOH2151

---

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE XUL B 1534

Chain	Residue
B	GLN97
B	GLN98
B	HIS99
B	TRP137
B	ARG170
B	ASP280
B	ASN281
B	HOH2015

---

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE XUL C 1534

Chain	Residue
C	GLN97
C	GLN98
C	HIS99
C	TRP137
C	ARG170
C	ASP280
C	ASN281
C	HOH2011

---

site_id	AC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE XUL A 1534

Chain	Residue
A	GLN97
A	GLN98
A	HIS99
A	TRP137
A	ARG170
A	ASP280
A	ASN281
A	HOH2009

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO B 1535

Chain	Residue
B	SER251
B	CYS252
B	PRO324
B	VAL325
B	ASP326
B	SER327

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	21
Details	Binding site: {}

Chain

Residue

Details

---