4B7B

Eg5-3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003777	molecular_function	microtubule motor activity
A	0005524	molecular_function	ATP binding
A	0007018	biological_process	microtubule-based movement
A	0008017	molecular_function	microtubule binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	BINDING SITE FOR RESIDUE ADP A 1364

Chain	Residue
A	PRO27
A	GLU118
A	CD1372
A	CL1378
A	HOH2007
A	HOH2016
A	HOH2182
A	HOH2184
A	HOH2185
A	GLN106
A	THR107
A	GLY108
A	THR109
A	GLY110
A	LYS111
A	THR112
A	PHE113

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD A 1365

Chain	Residue
A	HIS354
A	CL1375
A	HOH2177
A	HOH2178

---

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE CD A 1366

Chain	Residue
A	CYS25
A	VAL41
A	CYS43
A	CD1367
A	CL1374
A	CL1376
A	HOH2012
A	HOH2025

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CD A 1367

Chain	Residue
A	CYS25
A	ARG26
A	CD1366
A	CL1376
A	CA1388
A	HOH2011

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CD A 1368

Chain	Residue
A	CYS87
A	ASP91
A	HIS308
A	CO1383
A	HOH2049
A	HOH2050

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CD A 1369

Chain	Residue
A	GLU145
A	ASP149
A	CO1385
A	CO1386
A	HOH2092
A	HOH2093

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CD A 1370

Chain	Residue
A	LEU57
A	HIS141
A	ASP208
A	HOH2083
A	HOH2086

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD A 1371

Chain	Residue
A	CYS87
A	GLU313
A	CL1379
A	CL1380

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CD A 1372

Chain	Residue
A	THR112
A	ADP1364
A	HOH2072
A	HOH2184
A	HOH2185

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CD A 1373

Chain	Residue
A	THR203
A	HIS205
A	GLU209
A	CL1381
A	CL1382

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 1374

Chain	Residue
A	VAL41
A	CYS43
A	CD1366
A	HOH2025

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 1375

Chain	Residue
A	HIS354
A	CD1365
A	HOH2030
A	HOH2177

---

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 1376

Chain	Residue
A	GLY73
A	ALA74
A	CD1366
A	CD1367

---

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 1377

Chain	Residue
A	ASP59
A	SER61
A	GLU145
A	CO1385
A	HOH2193

---

site_id	BC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 1378

Chain	Residue
A	THR76
A	ADP1364
A	HOH2008

---

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 1379

Chain	Residue
A	TYR82
A	ARG83
A	GLN142
A	GLU313
A	CD1371

---

site_id	BC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 1380

Chain	Residue
A	ARG297
A	HIS308
A	GLU313
A	CD1371

---

site_id	BC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL A 1381

Chain	Residue
A	CL1391
A	HOH2187
A	HIS205
A	GLU209
A	GLU344
A	CD1373

---

site_id	CC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 1382

Chain	Residue
A	THR203
A	GLU209
A	CD1373
A	HOH2119
A	HOH2187

---

site_id	CC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CO A 1383

Chain	Residue
A	ASP91
A	LYS146
A	PRO310
A	GLU313
A	CD1368
A	HOH2050

---

site_id	CC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CO A 1384

Chain	Residue
A	ASP186
A	GLU247
A	HOH2138
A	HOH2189

---

site_id	CC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CO A 1385

Chain	Residue
A	ASP59
A	GLU145
A	CD1369
A	CL1377
A	HOH2190

---

site_id	CC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CO A 1386

Chain	Residue
A	GLU145
A	ASP149
A	CD1369
A	HOH2093
A	HOH2094
A	HOH2095

---

site_id	CC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CO A 1387

Chain	Residue
A	GLU166
A	SER291
A	HOH2106
A	HOH2158
A	HOH2159

---

site_id	CC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 1388

Chain	Residue
A	ARG26
A	PHE28
A	ASP251
A	PRO338
A	CD1367
A	HOH2021

---

site_id	CC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD A 1389

Chain	Residue
A	HIS38
A	ASP251
A	HOH2113
A	HOH2192

---

site_id	CC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD A 1390

Chain	Residue
A	GLU145
A	HOH2193

---

site_id	DC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CL A 1391

Chain	Residue
A	GLU345
A	CL1381
A	HOH2052
A	HOH2127
A	HOH2172
A	HOH2173
A	HOH2187

---

Functional Information from PROSITE/UniProt

site_id	PS00411
Number of Residues	12
Details	KINESIN_MOTOR_1 Kinesin motor domain signature. GKLnLVDLAGSE

Chain	Residue	Details
A	GLY259-GLU270

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00283","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---