4B6C
Structure of the M. smegmatis GyrB ATPase domain in complex with an aminopyrazinamide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006265 | biological_process | DNA topological change |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006265 | biological_process | DNA topological change |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE B5U A 1256 |
| Chain | Residue |
| A | ASN52 |
| A | SER126 |
| A | THR169 |
| A | HOH2007 |
| A | HOH2020 |
| A | HOH2030 |
| B | GLN195 |
| B | PHE199 |
| B | TYR253 |
| A | GLU56 |
| A | ASP79 |
| A | ARG82 |
| A | GLY83 |
| A | ILE84 |
| A | PRO85 |
| A | ASP97 |
| A | GLN102 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE B5U B 1256 |
| Chain | Residue |
| A | GLN195 |
| A | TYR253 |
| B | GLU48 |
| B | ASN52 |
| B | GLU56 |
| B | ASP79 |
| B | ARG82 |
| B | GLY83 |
| B | ILE84 |
| B | PRO85 |
| B | THR95 |
| B | VAL99 |
| B | MET100 |
| B | SER126 |
| B | HOH2004 |
| B | HOH2019 |
| B | HOH2034 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 1257 |
| Chain | Residue |
| A | ASP80 |
| A | GLY81 |
| A | THR167 |
| A | HOH2041 |
| A | HOH2042 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NA B 1257 |
| Chain | Residue |
| B | ASP80 |
| B | GLY81 |
| B | THR167 |
| B | HOH2010 |
| B | HOH2011 |
| B | HOH2043 |
| B | HOH2044 |
