4B6C
Structure of the M. smegmatis GyrB ATPase domain in complex with an aminopyrazinamide
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003677 | molecular_function | DNA binding |
A | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006265 | biological_process | DNA topological change |
B | 0003677 | molecular_function | DNA binding |
B | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
B | 0005524 | molecular_function | ATP binding |
B | 0006265 | biological_process | DNA topological change |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE B5U A 1256 |
Chain | Residue |
A | ASN52 |
A | SER126 |
A | THR169 |
A | HOH2007 |
A | HOH2020 |
A | HOH2030 |
B | GLN195 |
B | PHE199 |
B | TYR253 |
A | GLU56 |
A | ASP79 |
A | ARG82 |
A | GLY83 |
A | ILE84 |
A | PRO85 |
A | ASP97 |
A | GLN102 |
site_id | AC2 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE B5U B 1256 |
Chain | Residue |
A | GLN195 |
A | TYR253 |
B | GLU48 |
B | ASN52 |
B | GLU56 |
B | ASP79 |
B | ARG82 |
B | GLY83 |
B | ILE84 |
B | PRO85 |
B | THR95 |
B | VAL99 |
B | MET100 |
B | SER126 |
B | HOH2004 |
B | HOH2019 |
B | HOH2034 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE NA A 1257 |
Chain | Residue |
A | ASP80 |
A | GLY81 |
A | THR167 |
A | HOH2041 |
A | HOH2042 |
site_id | AC4 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE NA B 1257 |
Chain | Residue |
B | ASP80 |
B | GLY81 |
B | THR167 |
B | HOH2010 |
B | HOH2011 |
B | HOH2043 |
B | HOH2044 |