4B67
A. fumigatus ornithine hydroxylase (SidA), re-oxidised state bound to NADP and ornithine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0004499 | molecular_function | N,N-dimethylaniline monooxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0006696 | biological_process | ergosterol biosynthetic process |
| A | 0006879 | biological_process | intracellular iron ion homeostasis |
| A | 0010106 | biological_process | cellular response to iron ion starvation |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019290 | biological_process | siderophore biosynthetic process |
| A | 0031169 | biological_process | ferrichrome biosynthetic process |
| A | 0031172 | molecular_function | ornithine N5-monooxygenase activity |
| A | 0033214 | biological_process | siderophore-iron import into cell |
| A | 0044550 | biological_process | secondary metabolite biosynthetic process |
| A | 0070401 | molecular_function | NADP+ binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE FAD A 1492 |
| Chain | Residue |
| A | VAL45 |
| A | TRP90 |
| A | HIS91 |
| A | MET94 |
| A | MET101 |
| A | GLN102 |
| A | ILE103 |
| A | ARG144 |
| A | GLU166 |
| A | VAL168 |
| A | ALA209 |
| A | GLY46 |
| A | ILE210 |
| A | GLY211 |
| A | TYR407 |
| A | ARG409 |
| A | SER466 |
| A | LEU467 |
| A | LEU468 |
| A | NAP1493 |
| A | ORN1499 |
| A | HOH2001 |
| A | GLY48 |
| A | HOH2016 |
| A | HOH2032 |
| A | PRO49 |
| A | ALA50 |
| A | LEU82 |
| A | GLU83 |
| A | ARG84 |
| A | GLN85 |
| site_id | AC2 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE NAP A 1493 |
| Chain | Residue |
| A | SER99 |
| A | LYS100 |
| A | GLN102 |
| A | ARG144 |
| A | PRO217 |
| A | GLY253 |
| A | SER254 |
| A | GLY255 |
| A | GLN256 |
| A | SER257 |
| A | GLU260 |
| A | ARG279 |
| A | ASN323 |
| A | SER325 |
| A | ALA404 |
| A | THR405 |
| A | GLY406 |
| A | TYR407 |
| A | LEU467 |
| A | FAD1492 |
| A | ORN1494 |
| A | ORN1497 |
| A | HOH2017 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE ORN A 1494 |
| Chain | Residue |
| A | GLN102 |
| A | ILE103 |
| A | LYS107 |
| A | ASN293 |
| A | PHE296 |
| A | ASN323 |
| A | LEU467 |
| A | SER469 |
| A | NAP1493 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1495 |
| Chain | Residue |
| A | VAL365 |
| A | GLU366 |
| A | HIS367 |
| A | HIS368 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1496 |
| Chain | Residue |
| A | HIS126 |
| A | GLY129 |
| A | ARG130 |
| A | LEU131 |
| A | ILE132 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ORN A 1497 |
| Chain | Residue |
| A | PRO217 |
| A | SER218 |
| A | GLY219 |
| A | ILE362 |
| A | NAP1493 |
| A | HOH2023 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 1498 |
| Chain | Residue |
| A | GLU294 |
| A | TYR336 |
| A | MET339 |
| A | ARG343 |
| A | TRP352 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ORN A 1499 |
| Chain | Residue |
| A | ALA89 |
| A | HIS91 |
| A | FAD1492 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22928747","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
