4B5B

Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000271	biological_process	polysaccharide biosynthetic process
A	0005829	cellular_component	cytosol
A	0008879	molecular_function	glucose-1-phosphate thymidylyltransferase activity
A	0009058	biological_process	biosynthetic process
A	0009244	biological_process	lipopolysaccharide core region biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0019305	biological_process	dTDP-rhamnose biosynthetic process
A	0046872	molecular_function	metal ion binding
B	0000166	molecular_function	nucleotide binding
B	0000271	biological_process	polysaccharide biosynthetic process
B	0005829	cellular_component	cytosol
B	0008879	molecular_function	glucose-1-phosphate thymidylyltransferase activity
B	0009058	biological_process	biosynthetic process
B	0009244	biological_process	lipopolysaccharide core region biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0019305	biological_process	dTDP-rhamnose biosynthetic process
B	0046872	molecular_function	metal ion binding
C	0000166	molecular_function	nucleotide binding
C	0000271	biological_process	polysaccharide biosynthetic process
C	0005829	cellular_component	cytosol
C	0008879	molecular_function	glucose-1-phosphate thymidylyltransferase activity
C	0009058	biological_process	biosynthetic process
C	0009244	biological_process	lipopolysaccharide core region biosynthetic process
C	0016740	molecular_function	transferase activity
C	0016779	molecular_function	nucleotidyltransferase activity
C	0019305	biological_process	dTDP-rhamnose biosynthetic process
C	0046872	molecular_function	metal ion binding
D	0000166	molecular_function	nucleotide binding
D	0000271	biological_process	polysaccharide biosynthetic process
D	0005829	cellular_component	cytosol
D	0008879	molecular_function	glucose-1-phosphate thymidylyltransferase activity
D	0009058	biological_process	biosynthetic process
D	0009244	biological_process	lipopolysaccharide core region biosynthetic process
D	0016740	molecular_function	transferase activity
D	0016779	molecular_function	nucleotidyltransferase activity
D	0019305	biological_process	dTDP-rhamnose biosynthetic process
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	BINDING SITE FOR RESIDUE BBE A 400

Chain	Residue
A	SER41
A	GLU255
A	ILE256
A	HOH2037
A	HOH2070
A	HOH2076
A	THR42
A	LEU45
A	TYR113
A	TYR114
A	GLY115
A	PHE118
A	VAL250
A	ALA251

---

site_id	AC2
Number of Residues	13
Details	BINDING SITE FOR RESIDUE BBE B 400

Chain	Residue
B	SER41
B	THR42
B	LEU45
B	TYR113
B	GLY115
B	HIS119
B	ARG219
B	VAL250
B	ALA251
B	GLU255
B	ILE256
B	HOH2024
B	HOH2053

---

site_id	AC3
Number of Residues	15
Details	BINDING SITE FOR RESIDUE BBE C 400

Chain	Residue
C	SER41
C	LEU45
C	TYR113
C	TYR114
C	GLY115
C	PHE118
C	ARG219
C	VAL250
C	ALA251
C	GLU255
C	ILE256
C	HOH2028
C	HOH2031
C	HOH2068
C	HOH2075

---

site_id	AC4
Number of Residues	15
Details	BINDING SITE FOR RESIDUE BBE D 400

Chain	Residue
D	SER41
D	LEU45
D	TYR113
D	TYR114
D	GLY115
D	PHE118
D	ARG219
D	VAL250
D	ALA251
D	GLU255
D	ILE256
D	HOH2015
D	HOH2035
D	HOH2055
D	HOH2064

---

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL C 1294

Chain	Residue
C	HIS116
C	GLY220
C	HOH2030

---

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 1294

Chain	Residue
A	HIS116
A	GLY220

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 1294

Chain	Residue
B	HIS116
B	GLY218
B	ARG219
B	GLY220

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL D 1294

Chain	Residue
D	HIS116
D	ARG219
D	GLY220

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