4B3Z

Structure of the human collapsin response mediator protein-1, a lung cancer suppressor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004157	molecular_function	dihydropyrimidinase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005813	cellular_component	centrosome
A	0005819	cellular_component	spindle
A	0005829	cellular_component	cytosol
A	0005856	cellular_component	cytoskeleton
A	0006139	biological_process	nucleobase-containing compound metabolic process
A	0006208	biological_process	pyrimidine nucleobase catabolic process
A	0007399	biological_process	nervous system development
A	0010977	biological_process	negative regulation of neuron projection development
A	0015629	cellular_component	actin cytoskeleton
A	0016787	molecular_function	hydrolase activity
A	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
A	0016812	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A	0030425	cellular_component	dendrite
A	0030426	cellular_component	growth cone
A	0030496	cellular_component	midbody
A	0031005	molecular_function	filamin binding
A	0042802	molecular_function	identical protein binding
A	0043025	cellular_component	neuronal cell body
A	0043204	cellular_component	perikaryon
A	0051219	molecular_function	phosphoprotein binding
A	0071526	biological_process	semaphorin-plexin signaling pathway
A	0098793	cellular_component	presynapse
A	0098794	cellular_component	postsynapse
A	0150052	biological_process	regulation of postsynapse assembly
B	0004157	molecular_function	dihydropyrimidinase activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005813	cellular_component	centrosome
B	0005819	cellular_component	spindle
B	0005829	cellular_component	cytosol
B	0005856	cellular_component	cytoskeleton
B	0006139	biological_process	nucleobase-containing compound metabolic process
B	0006208	biological_process	pyrimidine nucleobase catabolic process
B	0007399	biological_process	nervous system development
B	0010977	biological_process	negative regulation of neuron projection development
B	0015629	cellular_component	actin cytoskeleton
B	0016787	molecular_function	hydrolase activity
B	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
B	0016812	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B	0030425	cellular_component	dendrite
B	0030426	cellular_component	growth cone
B	0030496	cellular_component	midbody
B	0031005	molecular_function	filamin binding
B	0042802	molecular_function	identical protein binding
B	0043025	cellular_component	neuronal cell body
B	0043204	cellular_component	perikaryon
B	0051219	molecular_function	phosphoprotein binding
B	0071526	biological_process	semaphorin-plexin signaling pathway
B	0098793	cellular_component	presynapse
B	0098794	cellular_component	postsynapse
B	0150052	biological_process	regulation of postsynapse assembly
C	0004157	molecular_function	dihydropyrimidinase activity
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005813	cellular_component	centrosome
C	0005819	cellular_component	spindle
C	0005829	cellular_component	cytosol
C	0005856	cellular_component	cytoskeleton
C	0006139	biological_process	nucleobase-containing compound metabolic process
C	0006208	biological_process	pyrimidine nucleobase catabolic process
C	0007399	biological_process	nervous system development
C	0010977	biological_process	negative regulation of neuron projection development
C	0015629	cellular_component	actin cytoskeleton
C	0016787	molecular_function	hydrolase activity
C	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
C	0016812	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C	0030425	cellular_component	dendrite
C	0030426	cellular_component	growth cone
C	0030496	cellular_component	midbody
C	0031005	molecular_function	filamin binding
C	0042802	molecular_function	identical protein binding
C	0043025	cellular_component	neuronal cell body
C	0043204	cellular_component	perikaryon
C	0051219	molecular_function	phosphoprotein binding
C	0071526	biological_process	semaphorin-plexin signaling pathway
C	0098793	cellular_component	presynapse
C	0098794	cellular_component	postsynapse
C	0150052	biological_process	regulation of postsynapse assembly
D	0004157	molecular_function	dihydropyrimidinase activity
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0005813	cellular_component	centrosome
D	0005819	cellular_component	spindle
D	0005829	cellular_component	cytosol
D	0005856	cellular_component	cytoskeleton
D	0006139	biological_process	nucleobase-containing compound metabolic process
D	0006208	biological_process	pyrimidine nucleobase catabolic process
D	0007399	biological_process	nervous system development
D	0010977	biological_process	negative regulation of neuron projection development
D	0015629	cellular_component	actin cytoskeleton
D	0016787	molecular_function	hydrolase activity
D	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
D	0016812	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D	0030425	cellular_component	dendrite
D	0030426	cellular_component	growth cone
D	0030496	cellular_component	midbody
D	0031005	molecular_function	filamin binding
D	0042802	molecular_function	identical protein binding
D	0043025	cellular_component	neuronal cell body
D	0043204	cellular_component	perikaryon
D	0051219	molecular_function	phosphoprotein binding
D	0071526	biological_process	semaphorin-plexin signaling pathway
D	0098793	cellular_component	presynapse
D	0098794	cellular_component	postsynapse
D	0150052	biological_process	regulation of postsynapse assembly

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Motif: {"description":"Required for interaction with FLNA","evidences":[{"source":"PubMed","id":"25358863","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	8
Details	Modified residue: {"description":"Phosphothreonine; by AURKA","evidences":[{"source":"PubMed","id":"19799413","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Modified residue: {"description":"3'-nitrotyrosine","evidences":[{"source":"UniProtKB","id":"P97427","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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